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Clarithromycin containing triple therapy Helicobacter pylori eradication compared with levofloxacin containing triple therapy

Comparing clarithromycin-based triple therapy Helicobacter pylori eradication with triple therapy containing levofloxacin

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015110224825N1
Enrollment
120
Registered
2016-02-09
Start date
2015-03-20
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Eradication of Helicobacter pylori. Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters

Interventions

Intervention 1: Control group: Panto Prazol 40 mg twice daily , amoxicillin 1g , clarithromycin 500 mg twice daily for 10 days. Intervention 2: Groups intervention: pantoprazole 40 mg twice daily, amo
Treatment - Drugs
Control group: Panto Prazol 40 mg twice daily , amoxicillin 1g , clarithromycin 500 mg twice daily for 10 days
Groups intervention: pantoprazole 40 mg twice daily, amoxicillin 1 g, levofloxacin 500 mg once daily for 10 days

Sponsors

Mazandaran University of medical sciences,Deputy of Research and Technology
Lead Sponsor

Eligibility

Sex/Gender
All
Age
76 Years to No maximum

Inclusion criteria

Inclusion criteria: inclusion criteria: All patients underwent endoscopy with duodenal ulcer or gastric or duodenal or stomach inflammation and Erosion referred to the clinic / office professor interviewed Sari hospital reported that Helicobacter pylori positive and study are older than 18 years Exclusion criteria: Pregnancy and breastfeeding; H. pylori eradication has already been received; During the last two weeks patients with PPI or H2 RA (histamine 2 receptor antagonist), or within the last 4 weeks have received antibiotics or bismuth; Concomitant use of anticoagulants; corticosteroids or ketoconazole; Patients with a history of stomach surgery; Patients with advanced disease confirmed and severe cardiac; pulmonary;Endocrine; chronic renal failure; chronic liver disease and cancer; alcohol consumption; With a history of peptic ulcer bleeding ulcer complications

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Eradication of Helicobacter pylor. Timepoint: 10 days after treatment,4 Weeks after treatment ppI,Four weeks after discontinuation of medication for respiratory test. Method of measurement: Through the breath test 14 C- UBT.

Secondary

MeasureTime frame
Headache?Dizziness?Confusion. Timepoint: During the course of treatment. Method of measurement: Calling and patient interview.;Bitter mouth. Timepoint: During the course of treatment. Method of measurement: Calling and patient interview.;Diarrhea-vomiting. Timepoint: During the course of treatment. Method of measurement: Calling and patient interview.;Skin complications. Timepoint: During the course of treatment. Method of measurement: Calling and patient interview.;Nausea , abdominal pain. Timepoint: During the course of treatment. Method of measurement: Calling and patient interview.;Side effects reported by patients include hypersensitivity reactions. Timepoint: During the course of treatment. Method of measurement: Calling and patient interview.;Constipation Decreased appetite. Timepoint: During the course of treatment. Method of measurement: Calling and patient interview.;Changes in taste. Timepoint: During the course of treatment. Method of measurement: Calling and patient interview.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMr. Dr Fakheri

Mazandaran University of Medical Sciences,Deputy of Research and Technology

GI-research-1@mazums.ac.ir+98 11332612468

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026