Skip to content

Comparison of the effect of co2 laser versus co2 laser and PRP on periorbital hyperpigmentation

Comparison of the effect of co2 laser versus co2 laser and PRP on periorbital hyperpigmentation

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015103118210N4
Enrollment
100
Registered
2015-11-29
Start date
2015-09-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

periorbital hyperpigmentation. Disorder of pigmentation, unspecified

Interventions

Intervention 1: co2 laser:is an ablative form of laser which affects superficial layer of the skin tissue. Intervention 2: PRP:platelet rich plasma is uptaken from their blood after centrifuge.
Treatment - Devices
Treatment - Other
co2 laser:is an ablative form of laser which affects superficial layer of the skin tissue
PRP:platelet rich plasma is uptaken from their blood after centrifuge

Sponsors

vice chancellor of Iran University of Medical Sciences research committee
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 50 Years

Inclusion criteria

Inclusion criteria: inclusion criteria:presence of POH;20-50 years old;women exclusion criteria:patients with platelet function impairment;severe thrombocytopenia(less than 50000);hemodynamic unstability;chronic hematologic disease(diabetes;chronic infection and blood dyscrasia);local inflammatory skin disorder or active herpes infection in site of procedure;consuming anticoagulant drugs or NSAIDs 48 hours before procedure;consuming topical corticosteroids in site of treatment 1 month before procedure;consuming systemic corticosteroids 2 weeks before procedure;fever;cancer(specially bone marrow or hematologic);level of hemoglubin lower than 10 gr in dl.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Periorbital hyperpigmentation. Timepoint: 3 monyhs and 6 months later. Method of measurement: photography.

Secondary

MeasureTime frame
Lightening the periorbital skin. Timepoint: 3 months and 6 months later. Method of measurement: photography.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Elham Behrangi

Iran University of Medical Sciences

behrangi.e@iums.ac.ir+98 21 6698

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026