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The effect of dexamethasone and epinephrine on the treatment of pharyngitis in children

Effect of inhaled epinephrine and injectable dexamethasone on the treatment of acute bronchiolitis in children who are treating with inhaled salbutamol

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015103023876N1
Enrollment
180
Registered
2015-10-30
Start date
2014-08-11
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bronchiolitis.

Interventions

Intervention 1: Intervention 1: dexamethasone mg / kg 6/0. Intervention 2: Intervention 2:inhaled epinephrine mg / kg15 / 0. Intervention 3: Control: distilled water as placebo.
Treatment - Drugs
Intervention 1: dexamethasone mg / kg 6/0
Intervention 2:inhaled epinephrine mg / kg15 / 0
Control: distilled water as placebo

Sponsors

Arak University of Medical Sceinces
Lead Sponsor

Eligibility

Sex/Gender
All
Age
2 Months to 2 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Ages 2 to 24 months; distress score greater than or equal to 6; the patient is first episode of acute bronchiolitis. Exclusion criteria: patient's unwillingness or inability to execute commands for the study; a history of allergic reaction to dexamethasone; a known heart or lung disease; premature birth (Age less than 36 weeks); immunodeficiency or immunosuppression; treatment with corticosteroids within 14 days recent Varsylay active or recent exposure to it.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Heart rate and breathing. Timepoint: Admission, 30, 60 and 120 minutes and 24 hours after the first dose. Method of measurement: Questionnaire.

Secondary

MeasureTime frame
Arterial oxygen saturation and respiratory distress. Timepoint: Admission, 30, 60 and 120 minutes and 24 hours after the first dose. Method of measurement: Questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Dorreh Fatemeh

Arak University of Medical sceinces

fatemeh_dorre@yahoo.com; rahenorayaneh@yahoo.com+98 86 3313 7550

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026