Indution of sedation for endoscopy in billiary disorders. Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
Conditions
Interventions
Intervention 1: Control Group: Placebo. Intervention 2: Nasal Dexmedetomidine 1 microgram per kg of body weight.
Placebo
Treatment - Drugs
Control Group: Placebo
Nasal Dexmedetomidine 1 microgram per kg of body weight
Sponsors
Iran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria's are: Age 18-65 years, both sex, having informed consent for entry to the study, ASA physical status class I-III Exclusion criteria's include: Age less than 18 and over than 65 years, ASA class over than III, history of open surgery in last week before endoscopy, chronic users of opiates & benzodiazepines, bradycardia (HR<45), systolic blood pressure less than 90 mmhg, cardiac conduction abnormality, patients using B-blockers & calcium channel blockers, patients with prolonged QT interval, active bleeding of upper or lower GI tract, patients with hemodynamic instability, pregnant patients, advanced liver insufficiency
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Level of sedation. Timepoint: Every two min after intervention. Method of measurement: Richmond agitation sedation scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| Total dose of midazolam and fentanyl useage. Timepoint: End of procedure. Method of measurement: Sum of these drugs in mg/kg. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSomayeh Allameh MD.
Iran University of Medical Sciences
Outcome results
None listed