Asthma. Status asthmaticus
Conditions
Interventions
Intervention 1: The intervention group will receive IV infusion Ketamine in 30 minutes (made by ROTEXMEDICA Company, Germany) with 0.3, 0.4, or 0.5 mg/kg doses in addition to the standard treatment. I
Treatment - Drugs
The intervention group will receive IV infusion Ketamine in 30 minutes (made by ROTEXMEDICA Company, Germany) with 0.3, 0.4, or 0.5 mg/kg doses in addition to the standard treatment
The control group will receive IV infusion Placebo in 30 minutes with the standard treatment
Sponsors
Isfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: Inclusion Criteria: patient's with mild to moderate asthma; patient's without any prohibition for using ketamine and history of allergic reaction. Exclusion Criteria: patient’s clinical condition worsened during the study; patient's needed mechanical ventilation; patient's who show ketamine side effects.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Peak Expiratory Flow Rate. Timepoint: at the study begining and every 30 minutes till 1 houre. Method of measurement: peak Flow Meter. | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical signs. Timepoint: at the study begining and every 30 minutes till 1 houre. Method of measurement: Clinical Examination.;Ketamine Complications. Timepoint: at the study begining and every 30 minutes till 1 houre. Method of measurement: Clinical Examination. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMehrdad Esmailian
Isfahan University of Medical Sciences
Outcome results
None listed