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prednisolone effect in optic neutitis

comparing the efficacy of IV methyprednisolone plus oral prednisolone therapy with IV methyprednisolone therapy alone in the treatment of acute demyelinating optic neuritis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015102724734N1
Enrollment
60
Registered
2016-04-18
Start date
2015-11-20
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

optic neuritis. demyelinating diseases of the central nervous system

Interventions

Intervention 1: intervention group:Tab prednisolone 50 mg po for 10 days,Made by:Abureihan pharmacy. Intervention 2: control group:Tab placebo po daily for 10 days,Made by: Jondishapur Ahvaz Univers
Treatment - Drugs
Placebo
intervention group:Tab prednisolone 50 mg po for 10 days,Made by:Abureihan pharmacy
control group:Tab placebo po daily for 10 days,Made by: Jondishapur Ahvaz University of Pharmacy Sciences

Sponsors

vice chancellor for research,Ahvaz jundishapur University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to 50 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria:patient 15 to 50 years old reffered with optic neuritis" that their visual acuity decreased above 50% Exclusion criteria:side effect such as gastrointestinal bleeding ,...during usage of methyprednisolone puls and oral prednisolone" patients with diabet

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Visual acuity. Timepoint: before.first day after end of intervention, 1month.3months afte intervention. Method of measurement: snellen chart.

Secondary

MeasureTime frame
Color vision. Timepoint: before,first day after end of intervention ,1month,3months after intervention. Method of measurement: farnsworth d15.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyed Ehsan Mohammad Yani Nejad

Ahvaz University Of Medical Sciences

ehsanneuro@Gmail.com+98 61 3374 3012

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026