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Effect of pentoxifylline in myocardial infartion

effect of pentoxifylline in ameliorating myocardial injury in patients with anterior myocardial infartion undergoing thrombolytic therapy :randomized controlled trial,a pilot study

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015102624722N1
Enrollment
90
Registered
2016-01-17
Start date
2015-12-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

myocardial infarction. Diseases of the circulatory ystem

Interventions

Intervention 1: Intervention group:1200 mg loading dose of pentoxiphylline table(3 tablet 400 mg )trance oral without continuous Hakim Manufact
Treatment - Drugs
Intervention group:1200 mg loading dose of pentoxiphylline table(3 tablet 400 mg )trance oral without continuous Hakim Manufactory
control group:no intervention

Sponsors

Cardiovascular Research Center, Tabriz University Of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 139 Years

Inclusion criteria

Inclusion criteria: inclusion criteria: patients with over 18 year; patients with acute anterior myocardial infarction; patients undergoing thrombolytic therapy exclusion criteria: history of coronary artery by pass graft; history of myocardial infarction; history of renal failure; sensitivity to aspirin,clopidogrel or pentoxifylline; cardiogenic shock

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Check of cardiac enzymes(cpk ,CK-MB). Timepoint: check at base then every 8 hour until 48 hour. Method of measurement: Enzymes chec.

Secondary

MeasureTime frame
The st-resolution rate at 90 minute after given thrombolytic. Timepoint: 90 minute after given thrombolytic. Method of measurement: percent of st decline.

Countries

Iran (Islamic Republic of)

Contacts

Public Contactrasol zohouri

madani educational,theraputical and research cardiovascular center

MadaniHeartgroup@gmail.com; rasol.zohori2@gmail.com+98 41 3336 3880

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026