Postpartum hemorrhage. Postpartum haemorrhage
Conditions
Interventions
Intervention 1: Group A: Cesarean section will do under spinal anesthesia. Patients receive 400 micrograms of misoprostol rectal (as 2 tablets of 200 mcg). Intervention 2: Groupe B: Cesarean section w
Treatment - Drugs
Group A: Cesarean section will do under spinal anesthesia. Patients receive 400 micrograms of misoprostol rectal (as 2 tablets of 200 mcg).
Groupe B: Cesarean section will done under spinal anesthesia. Patients receive Tranexamic acid, 10mg/kg 30 minutes before operation as intravenous infusion during 20 minutes.
Group C: Cesarean section will do under spinal anesthesia. Patients will not receive any treatments except standard and usual therapy.
Sponsors
Vice Chancellor for Research of Semnan University of Medical Science
Eligibility
Sex/Gender
Female
Age
15 Years to 45 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Candidates for elective cesarean section; gestational age 37 weeks or more; singleton pregnancy with cephalic presentation. Exclusion criteria: Preeclampsia; multiple pregnancies; premature birth; prolonged rupture of the membranes; abnormal placental-binding; systemic diseases; sensitivity to prostaglandins.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Volume of Blood Loss. Timepoint: During surgery. Method of measurement: Measuring of blood lost and counting of blood soaked gauze pieces. | — |
Secondary
| Measure | Time frame |
|---|---|
| Hematocrite and Hemoglubin. Timepoint: 24 horses after surgery. Method of measurement: Laboratory test. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Roya Mahdavi Anaraki
Semnan University of Medical Sciences
Outcome results
None listed