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The effect of bupropion on the improvement of sexual side effects caused by SSRI use

Investigating the effect of bupropion on the sexual function of patients with sexual side effects caused by SSRI use, a double-blind clinical trial

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20151022024650N2
Enrollment
60
Registered
2023-01-01
Start date
2023-01-21
Completion date
Unknown
Last updated
2023-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sexual dysfunction. Sexual dysfunction not due to a substance or known physiological condition

Interventions

Intervention 1: Intervention group: after justifying the patients and providing the necessary training, 75 mg bupropion tablets are prescribed once a day during the study (8 weeks). Intervention 2: Co

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
15 Years to 55 Years

Inclusion criteria

Inclusion criteria: Patients under SSRI treatment for at least three consecutive months; having sexual dysfunction for at least the last two months; married and sexually active; Age range 15-55 years; stable vital signs.

Exclusion criteria

Exclusion criteria: The presence of digestive problems such as severe nausea and vomiting and SSRI intolerance; The presence of concurrent chronic liver or kidney disease; The presence of any anatomical problem of the reproductive system; The existence of any severe or relatively severe hormonal disorder; Absence of pregnancy; Lack of breastfeeding; Non-participation in the study.

Design outcomes

Primary

MeasureTime frame
Measuring sexual satisfaction. Timepoint: Once a Month. Method of measurement: Hudson's Standardized Sexual Satisfaction Questionnaire (ISS).;Measuring sexual performance. Timepoint: Once a Month. Method of measurement: Rozen Standardized Women's Sexual Performance Questionnaire (FSFI).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Elham Ghasemi

Tabriz University of Medical Sciences

dr.egh92@gmail.com+98 939 667 6405

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026