The effect of vitamin C on thyroid function

The effect of vitamin C supplementation on thyroid function in patients with primary hypothyroidism

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2015102124634N1

Enrollment

Registered

2016-05-31

Start date

2015-03-16

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary hypothyroidism. Other specified hypothyroidism, Hypothyroidism, unspecified

Interventions

8 weeks treatment with levothyroxine dose control with the Company, iran hormone and 8 weeks treatment with levothyroxine plus 500 milligrams of vitamin C daily morning fasting in the 200 cc model man

Treatment - Drugs

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: TSH level between 0.5 and 4.5 micrograms per liter; taking levothyroxine dose for at least 6 months without changes. Exclusion criteria: thyroid cancer; pregnant or nursing; taking OCP or estrogen and testosterone during 3 months ago; chronic GI disease.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
T3, T4. Timepoint: Arrival, 8 weeks after treatment. Method of measurement: In ng / dl using a blood test.	—

Secondary

Measure	Time frame
TSH. Timepoint: Arrival, 8 weeks after treatment. Method of measurement: In U/ml using a blood test.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Kazemzad Hamid

Arak University of Medical sceinces

h.kazemzad@arakmu.ac.ir; rahenorayaneh@yahoo.com+98 86 3312 4922

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026