Thyme combined effect of triple therapy regimen compared with the standard regimen alone in eradication of Helicobacter pylori infection

Thyme combined effect of triple therapy regimen compared with the standard regimen alone in eradication of Helicobacter pylori infection in patients who referred with upper gastrointestinal symptoms.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2015102024625N1

Enrollment

Registered

2016-02-17

Start date

2015-08-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Helicobacter pylori eradication. Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters

Interventions

Intervention 1: Control group will receive a regimen including pantoprazole tablets 40 mg two times per day, amoxicillin 1 g capsule two times per day, clarithromycin 500 mg capsules two times per day

Placebo

Treatment - Drugs

Control group will receive a regimen including pantoprazole tablets 40 mg two times per day, amoxicillin 1 g capsule two times per day, clarithromycin 500 mg capsules two times per day and a placebo w

Intervention group will receive a regimen including pantoprazole tablets 40 mg two times per day, amoxicillin 1 g capsule two times per day, clarithromycin 500 mg capsules two times per day and thyme

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inclusion Criteria: Positive result for urea breath test Exclusion criteria: Receiving of Helicobacter pylori eradication therapy during past six months.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Negative urea breath test. Timepoint: Six weeks after initiation of interventions. Method of measurement: Urea breath test.	—

Secondary

Measure	Time frame
Eradication of Helicobacter pylori infection. Timepoint: Six weeks after interventions. Method of measurement: Urea breath test.	—

Countries

Iran (Islamic Republic of)

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026