The effect of a new bone material in the treatment of bony defects caused by periodontal disease

Comparative effect of Porous Titanium Granules and Bio-Oss on bone regeneration in periodontal defects

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2015102024622N1

Enrollment

Registered

2015-11-22

Start date

2015-11-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic periodontitis. Chronic Periodontits

Interventions

Intervention 1: treatment using porous titanium granules (PTG) in the test group. surgery is done using a full thickness with a distance of one tooth at each side of the defect. after flap reflection

Treatment - Other

Treatment - Drugs

treatment using porous titanium granules (PTG) in the test group. surgery is done using a full thickness with a distance of one tooth at each side of the defect. after flap reflection a complete debr

treatment using Bio-Oss in the control group. surgery is done using a full thickness with a distance of one tooth at each side of the defect. after flap reflection a complete debrement of the defect w

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with at least one vertical defect assessed by clinical and radiographic evaluation Patients with no systemic disease

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Depth of the defect. Timepoint: at the first surgery and 6 months later at a re-entry surgery. Method of measurement: using a periodontal probe.;Width of the defect. Timepoint: at the first surgery and 6 months later at a re-entry surgery. Method of measurement: using a periodontal probe.	—

Secondary

Measure	Time frame
Keratinized tissue. Timepoint: at the first surgery and 6 months later at a re-entry surgery. Method of measurement: using a periodontal probe.;Plaque index. Timepoint: at the first surgery and 6 months later at a re-entry surgery. Method of measurement: using a periodontal probe.;Gingival recession. Timepoint: at the first surgery and 6 months later at a re-entry surgery. Method of measurement: using a periodontal probe.;Bleeding on probing. Timepoint: at the first surgery and 6 months later at a re-entry surgery. Method of measurement: using a periodontal probe.;Clinical attachment level. Timepoint: at the first surgery and 6 months later at a re-entry surgery. Method of measurement: using a periodontal probe.;Pocket depth. Timepoint: at the first surgery and 6 months later at a re-entry surgery. Method of measurement: using a periodontal probe.	—

Measure

Time frame

Keratinized tissue. Timepoint: at the first surgery and 6 months later at a re-entry surgery. Method of measurement: using a periodontal probe.;Plaque index. Timepoint: at the first surgery and 6 months later at a re-entry surgery. Method of measurement: using a periodontal probe.;Gingival recession. Timepoint: at the first surgery and 6 months later at a re-entry surgery. Method of measurement: using a periodontal probe.;Bleeding on probing. Timepoint: at the first surgery and 6 months later at a re-entry surgery. Method of measurement: using a periodontal probe.;Clinical attachment level. Timepoint: at the first surgery and 6 months later at a re-entry surgery. Method of measurement: using a periodontal probe.;Pocket depth. Timepoint: at the first surgery and 6 months later at a re-entry surgery. Method of measurement: using a periodontal probe.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSamareh Kafilzadeh

Hamedan University of Medical Sciences

sn4014@yahoo.com+81 8247464

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026