Functional dyspepsia. Functional dyspepsia
Conditions
Interventions
Intervention 1: Intervention group: Probiotic: One sachet of Rotflor containing Lactobacillus reuteri, taken once daily dissolved in water for 4 weeks. PPI: Standard dose of pantoprazole based on the
for weight 40 kg and above: 40 mg once daily). Intervention 2: Control group: PPI: Standard dose of pantoprazole based on the child's age and weight (for weight 15 kg to less than 40 kg: 20 mg once da
for weight 40 kg and above: 40 mg once daily).
Sponsors
Semnan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
7 Years to 12 Years
Inclusion criteria
Inclusion criteria: Diagnosis of functional dyspepsia based on the Rome IV diagnostic criteria.
Exclusion criteria
Exclusion criteria: Organic gastrointestinal diseases Use of antibiotics or any probiotic products in the 4 weeks leading up to the start of the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Common symptoms of dyspepsia include abdominal pain, bloating, early satiety, nausea, vomiting, and diarrhea. Timepoint: 28 days after treatment. Method of measurement: ROME IV score. | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of life. Timepoint: 28 days after treatment. Method of measurement: PedsQL™ Gastrointestinal Symptoms Module. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMehri Ayati
Semnan University of Medical Sciences
Outcome results
None listed