Osteoarthritis of knee. Osteoarthritis of knee
Conditions
Interventions
Intervention 1: Intervention group one: Corticosteroid, 40 mg Methylprednisolone, one time injection inside knee joint at suprapatellar recess. Intervention 2: Intervention group: Intervention group t
Sponsors
Iran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
40 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients with mild to moderate osteoarthritis of the knee (Kellgren Lawrence grade I, II and III) Knee pain for at least six months
Exclusion criteria
Exclusion criteria: History of knee surgery or fracture History of knee meniscus or ligaments tear (ACL/PCL/MCL/LCL) Pregnancy History of allergic reaction to Corticosteroid, Dextrose or Ozone Infection at the injection site Uncontrolled diabetes History of systemic inflammatory or connective tissue disease History of knee injections in the last three months History of gout Secondary knee osteoarthritis Contraindications of ozone therapy (deficiency G6PD, uncontrolled hyperthyroidism, leukemia)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual Analog Scale (VAS). Timepoint: Before intervention, 1 and 8 weeks after intervention. Method of measurement: Visual Analogue Scale Questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). Timepoint: Before intervention and 1, 8 weeks after intervention. Method of measurement: Questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Arash Babaei
Iran University of Medical Sciences
Outcome results
None listed