Ultrasound-guided Prolotherapy, Oxygen-ozone and corticosteroid injection for treatment of Pes Anserine bursitis

Ultrasound-guided Prolotherapy, Oxygen-ozone and corticosteroid injection for treatment of Pes Anserine bursitis: A randomized, double-blind, multi-center study.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20151017024572N22

Enrollment

Registered

2020-07-31

Start date

2020-08-20

Completion date

Unknown

Last updated

2020-08-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pes Anserine bursitis. Other bursitis of knee

Interventions

Intervention 1: Intervention group one: Corticosteroid, 40 mg Methylprednisolone, one time injection at the site of Pes Anserine bursa. Intervention 2: Intervention group two: Ozone (O2-O3), 12 micro-

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Tenderness in Pes Anserine bursa location Negative physical examination for knee ligaments tear including valgus stress test Grade II or III Kellgren-Lawrence for knee osteoarthritis

Exclusion criteria

Exclusion criteria: History of knee surgery or fracture Less than 18 years old History of knee meniscus or ligaments tear (ACL/PCL/MCL/LCL) Pregnancy History of allergic reaction to Corticosteroid, Dextrose or Ozone Infection at the injection site Uncontrolled diabetes History of systemic inflammatory or connective tissue disease History of burs injections in the last six months History of gout

Design outcomes

Primary

Measure	Time frame
Visual Analog Scale (VAS). Timepoint: Before intervention, 1 and 8 weeks after intervention. Method of measurement: Visual Analogue Scale Questionnaire.;Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). Timepoint: Before intervention and 1, 8 weeks after intervention. Method of measurement: Questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Arash Babaei

Iran University of Medical Sciences

arashbabaie@gmail.com+98 21 4128 9221

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026