Primery gonrthrosis,bilatral. Bilateral primary osteoarthritis of knee
Conditions
Interventions
Intervention 1: Intervent group: three times ozon injectione with a one-week interval by a physician and rhabilition spesialist under the ultrasound guide in the knee joint through a supra patellar
Sponsors
Iran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
40 Years to 75 Years
Inclusion criteria
Inclusion criteria: Patients with mild to moderate OA of the knee (Kellgren Lawrence grade I, II and III) Knee pain for at least six months Age 40 to 75 years old The absence of any acute or chronic infection No pregnancy or lack of planning to get pregnant No history of any intra articular knee injection in three months ago The absence of inflammatory articular disease or secondary osteoarthritis No history of knee surgery (3 months ago) No severe underlying disease such as uncontrolled diabetes Use of anticoagulants Lack of daily use of opioid and non opioid analgesics Absence of contraindications of ozone therapy (deficiency G6PD, uncontrolled hyperthyroidism, leukemia).
Exclusion criteria
Exclusion criteria: The willingness of patients to exit from the study at any stage of the study Not coming patients for follow up and evaluation during the follow up period Daily use of any type of analgesic medication by patients during the follow up period Occurring a pathology in the knee, such as meniscus tear during the follow up period Occurring 4th and 7th inclusion criteria, during the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The severity of pain. Timepoint: Zero, one, four and twelve weeks after. Method of measurement: Visual Analog Scale(VAS).;The severity of symptoms and functional limitations. Timepoint: Zero, one, four and twelve weeks after. Method of measurement: By using WOMAC questioner.;Sonographic criteria (efusion). Timepoint: Zero, one, four and twelve weeks after. Method of measurement: By using sonographic device.;Range of motion. Timepoint: Zero, one, four and twelve weeks after. Method of measurement: Goniometer.;Side effects. Timepoint: one, four weeks after. Method of measurement: Physical examination. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Vajihe Alishahi
Iran University of Medical Sciences
Outcome results
None listed