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Evaluation of the Effect of intravenous paracetamol on perioperative pain in coronary artery bypass graft surgery

Evaluation of effect of paracetamol on post-operative pain in coronary artery bypass graft surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015101613181N2
Enrollment
110
Registered
2015-11-17
Start date
2014-05-31
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Perioperative pain. Other specified complications of cardiac and vascular prosthetic devices, implants and grafts

Interventions

Intervention 1: In paracetamol group 15 minutes before induction of anesthesia 1 g intravenous paracetamol in 50 cc normal saline solution was infused to the patient within 15 minutes. Next dose of p
Prevention
In paracetamol group 15 minutes before induction of anesthesia 1 g intravenous paracetamol in 50 cc normal saline solution was infused to the patient within 15 minutes. Next dose of paracetamol was
In the control group at all stages of paracetamol injection instead of paracetamol equal volume of normal saline was used.

Sponsors

Isfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 70 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria: Inclusion criteria for the study were: undergoing elective surgery CABG, the individual agreement to participate in the study, age 40 to 70 years, not having liver failure (Serum bilirubin greater than 1.8 mg per deciliter and aspartate and alanine aminotransfraz more than 1.5 times of the upper limit of normal), not having renal failure (serum creatinine greater than 2 mg per deciliter), not addictive to opioid drugs and psychotropic substances, and having cardiac ejection fraction greater than 30%., Exclusion criteria for the study: Excessive bleeding after surgery (more than 150 ml for the first two hours), having other surgeries in addition to coronary artery bypass surgery such as repair or replacement of heart valves, repeated surgery, and the need for aortic balloon support.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Pain. Timepoint: during study. Method of measurement: VAS and FAS.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMojtaba Mansouri

Isfahan Univrsity of Medical Sciences

mansouri@med.mui.ac.ir+98 31 3775 0252

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026