Ovarian rejuvenation in diminished ovarian reserve patients. Primary ovarian failure
Conditions
Interventions
Intervention 1: Frist intervention group: 15 infertile women with diminished ovarian reserve aged between 20-48 years were administered by gonadotropin (Cinnal f, 75 IU, CinnaGen Co.) with the dose of
17 ml of peripheral venous blood was drawn in the syringe that contained 3 ml of Acid Citrate A Anticoagulant solution (ACD-A) and centrifuged immediately at 1600 g for 10 min. The blood was divided i
Sponsors
Deputy of Research and Development, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Eligibility
Sex/Gender
Female
Age
20 Years to 48 Years
Inclusion criteria
Inclusion criteria: Female infertility Diminish ovarian reserve (AMH<1.1 and AFC< 5-7) 20 to 48 years
Exclusion criteria
Exclusion criteria: Uterin anomaly Polycystic Ovarian Syndrome Male factor Tubal factor
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Increase Anti-Müllerian hormone level. Timepoint: At the beginning of the study, every month up to 3 months. Method of measurement: Lab Test. | — |
Secondary
| Measure | Time frame |
|---|---|
| Antral follicular count. Timepoint: 1 to 4 months later. Method of measurement: Transvaginal sonography.;Spontaneous pregnancy. Timepoint: 3 months later. Method of measurement: Lab test.;Entering assisted reproductive cycle. Timepoint: Once the AMH increases or the patient insists on doing assisted reproductive cycle. Method of measurement: Lab test. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAbbas Aflatoonian
Yazd University of Medical Sciences
Outcome results
None listed