Systemic lupus erythematosus. Systemic lupus erythematosus, unspecified
Conditions
Interventions
Intervention 1: Intervention group: 45 patients with moderate to severe chronic periodontitis, at the beginning of the intervention, complete periodontal examinations, scaling and smoothing of root su
Sponsors
Yazd University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Definitive confirmation of systemic lupus erythematosus by a fellow rheumatologist and the condition of the disease is controlled Confirmation of moderate to severe generalized chronic periodontitis Have at least 20 teeth There is no evidence of heart valve involvement, congenital disorder, or a history of previous endocarditis requiring antibiotic prophylaxis. The patient's dose of corticosteroids should be below 20 mg of hydrocortisone or its equivalent A recent blood test is available based on the patient's neutrophil count above 1000 Evaluation of coagulation factors in case of thrombocytopenia in the patient's blood test Not taking aspirin and anticoagulants in the last month Do not take any antibiotics for 3 months before the start of the study Do not take a cytotoxic drug such as cyclophosphamide in the last month Non-long-term use of drugs affecting periodontal status (anticonvulsants, calcium channel blockers, etc.) during the 3 months before the start of the study Complete the consent form
Exclusion criteria
Exclusion criteria: Having another systemic disease such as primary Sjogren's syndrome, diabetes, cardiovascular disease, history of radiation therapy or chemotherapy Antiphospholipid syndrome Pregnancy in a recent year History of periodontal treatment in the last 6 months Smoking
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Probing depth. Timepoint: At the beginning of the study (before the intervention) and 3 months after the start of the study. Method of measurement: With Williams Probe.;Clinical attachment loss. Timepoint: At the beginning of the study (before the intervention) and 3 months after the start of the study. Method of measurement: With Williams Probe.;Bleeding index. Timepoint: At the beginning of the study (before the intervention) and 3 months after the start of the study. Method of measurement: Percentage of bleeding around the entire teeth after 30 seconds after probing.;Plaque index. Timepoint: At the beginning of the study (before the intervention) and 3 months after the start of the study. Method of measurement: Percentage of plaque accumulation around tooth surfaces after evaluation with a disclosingagent.;Systemic lupus erythematosus disease activity index. Timepoint: At the beginning of the study (before the intervention) and 3 months after the start of the study. Method of measurement: Numerically from 0 to 105 with Q * MD software.;C-Reactive protein (CRP). Timepoint: At the beginning of the study (before the intervention) and 3 months after the start of the study. Method of measurement: Record patient test information.;Erythrocyte Sedimentation Rate (ESR). Timepoint: At the beginning of the study (before the intervention) and 3 months after the start of the study. Method of measurement: Record patient test information. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFahimeh Rashidi
Yazd University of Medical Sciences
Outcome results
None listed