Comparison of the role of intrapleural pethidine injection with intravenous morphine in the management of post-operative pain after open cholesystectomy

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20151012024493N3

Enrollment

Registered

2019-03-10

Start date

2018-03-21

Completion date

Unknown

Last updated

2019-03-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Open cholecystectomy. Cholecystitis

Interventions

Intervention 1: Control group: At the end of the surgery,the patient receives the neuromuscular reversal agents and the infusion of propofol and remifental continues.A metallic epidural needle is inse

Eligibility

Sex/Gender

All

Age

18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Candidate for elective open cholecystectomy surgery ASA class = 1 or 2 BMI between 18 to 30 kg/m2

Exclusion criteria

Exclusion criteria: History of addiction History of prolonged analgesic consumption History of thoractomy

Design outcomes

Primary

Measure	Time frame
Amount of consumed morphine during the first 12 hours of postoperative period. Timepoint: 12 hours after surgery. Method of measurement: Documented total amount of injected morphine in milligrams.;The time of first demand for morphine during the postoperative period. Timepoint: The time of first patient's demand for morphine during the postoperative period in minutes. Method of measurement: chronometer.	—

Measure

Time frame

Amount of consumed morphine during the first 12 hours of postoperative period. Timepoint: 12 hours after surgery. Method of measurement: Documented total amount of injected morphine in milligrams.;The time of first demand for morphine during the postoperative period. Timepoint: The time of first patient's demand for morphine during the postoperative period in minutes. Method of measurement: chronometer.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactParisa Sezari

Shahid Beheshti University of Medical Sciences

parissasezari@yahoo.com+98 21 5542 4040

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026