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Effectiveness of acute postoperative pain management of oral Lamotrigine after impacted third molar surgery.

Postoperative pain management after impacted third molar surgery with perioperative oral Lamotrigine.

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT201510111674N12
Enrollment
50
Registered
2015-10-21
Start date
2015-10-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Impacted teeth. An impacted tooth is a tooth that has failed to erupt because of obstruction by another tooth.

Interventions

Intervention 1: Drug is administered with dose of 200 tablets of Lamotrigine orally with about 20 cc of water are given to the patient's study 1 hours before surgery. Intervention 2: The second group
Treatment - Drugs
Drug is administered with dose of 200 tablets of Lamotrigine orally with about 20 cc of water are given to the patient's study 1 hours before surgery.
The second group or control group received placebo with about 20 cc of water 1 hours before surgery.

Sponsors

Vice-Chancellery of Research and Technology, Shiraz University Of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to 25 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria included: The patients with systemic disease and no history of drug use, and willingness to cooperate in this study are enrolled? Exclusion criteria included known allergy to the study drug, hepatic and renal dysfunction and lack of signed informed consent will be excluded.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Intensity of postoperative pain. Timepoint: Immediately after surgery to 12 hours after surgery. Method of measurement: VAS.

Secondary

MeasureTime frame
Patient's level of satisfaction. Timepoint: Immediately after surgery to 12 hours after surgery. Method of measurement: poor (0), moderate (1), good (2), and excellent (3).;Post-operative complications of Lamotrigine. Timepoint: Immediately after surgery to 12 hours after surgery. Method of measurement: Nursing reports.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHamid Reza Eftekharian

Shiraz School of Dentistry

eftekharhr@sums.ac.ir+98 71 3648 3783

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026