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Effect of mitomycin C in glaucoma shunt surgery

Evaluation the Efficacy of Ahmed Glaucoma Valve Implantation with and with out Mitomycin C(MMC) during surgery in patients with glaucoma

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015101024459N1
Enrollment
60
Registered
2016-01-14
Start date
2015-11-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

glaucoma. Glaucoma

Interventions

Intervention 1: After informing the patients about the procedure, and signing a consent form, the patients were randomly divided in two groups to receive intra-operative MMC or a Placebo. The surgical
Treatment - Drugs
After informing the patients about the procedure, and signing a consent form, the patients were randomly divided in two groups to receive intra-operative MMC or a Placebo. The surgical procedure consi

Sponsors

Farabi Eye Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
17 Years to No maximum

Inclusion criteria

Inclusion criteria: inclusion criteria:Uncontrolled glaucoma patients under 18 years that are candidates for shunt surgery exclusion criteria:Patients under 18 years; active iris neovascularization; anterior staphyloma; Breast-feeding and pregnancy; Previous shunt surgery; corneal lesions Which prevents IOP measurement

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Intra oclar pressure. Timepoint: before intervention and one day and one week and one month and 3 months and 6 months and 12 months after intervention. Method of measurement: goldmann tonometer.

Secondary

MeasureTime frame
Tube-corneal contact. Timepoint: one day and one week and one month and 3 months and 6 moths and 12 months after intervention. Method of measurement: slit lamp exam.;The number of drugs used to control intra ocular pressure. Timepoint: one day and one week and one month and 3 months and 6 moths and 12 months after intervention. Method of measurement: history.;Hyphema. Timepoint: one day and one week and one month and 3 months after intervention. Method of measurement: slit lamp exam.;Retraction of tube from anterior chamber. Timepoint: one day and one week and one month and 3 months and 6 moths and 12 months after intervention. Method of measurement: slit lamp exam.;Tube/implant exposure. Timepoint: one day and one week and one month and 3 months and 6 moths and 12 months after intervention. Method of measurement: slit lamp exam.;Flat chamber/transient hypotony. Timepoint: one day and one week after intervention. Method of measurement: goldmann tonometer.;Choroidal effusion. Timepoint: one day and one week and one month and 3 months and 6 moths and 12 months after intervention. Method of measurement: ocular ultrasonography.;Blocked tube. Timepoint: one day and one week and one month and 3 months and 6 moths and 12 months after intervention. Method of measurement: slit lamp exam.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDoctor Ghasem Fakhraee

Farabi Eye Hospital

drfakhraee@yahoo.com+98 215540000314

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026