General Anesthesia. Intravenous Anesthetics, Other and Unspecified General Anesthetics, Local Anesthetics
Conditions
Interventions
Intervention 1: Nerve block with TAP Methods with Marcaine in the intervention group. Intervention 2: Nerve block with TAP Methods with Normal Saline in the control group.
Prevention
Nerve block with TAP Methods with Marcaine in the intervention group
Nerve block with TAP Methods with Normal Saline in the control group
Sponsors
Vice Chancellor For Research of University, Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Age 18-60 years, BMI<30, Stage 1 and 2 ASA, Surgery time less than 2 hours; Absence of systemic disease such as (heart or lung disease and serious liver-Kidney disease); Absence of contraindications to epidural anesthesia (coagulopathies, infection at needle insertion site, the patient's lack of cooperation, absence consent); Absence of any contraindications to perform Block; Absence of a history of immunosuppressive and corticosteroid drugs; Absence of a history of drug addiction and smoking. Exclusion criteria: Failing to block, Incidence of complications during surgery and laparotomy for any reason, Prolongation of operation (more than 2 hours)
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain. Timepoint: Immediately, 6, 12, 24 hours after discharge from recovery. Method of measurement: Visualized Analogue Scale.;The Subjective Success Rate of Block. Timepoint: 30 minute. Method of measurement: Check the skin sensation of the same area of block in the epigastric and umbilical and groin.;Objective success rate of blockage for anesthesia by injection and deposition of the sediment material (Marcaine) between the layers of muscle (IOM and TAM). Timepoint: During of surgery. Method of measurement: Ultrasound sonography. | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood Sugar ,WBC , CRP , Cortisol, TNF-a and IL-1 level of serum. Timepoint: Before induction of anesthesia and 6 and 24 hours after extubation of patient. Method of measurement: Blood Exam. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFarhad Rahimi
Anesthesiology Department, Dr Shariati Hospital, Tehran University of Medical Sciences
Outcome results
None listed