ventilator associated pneumonia. other acute lower respiratory infections
Conditions
Interventions
Intervention 1: In control group, oral care protocol include, suction, oral assessment, brushing and rubbing saturated oral foam application of chlorhexidine 0/2% 10ml on gum, mucosa, teeth, hard pal
Prevention
Treatment - Drugs
In control group, oral care protocol include, suction, oral assessment, brushing and rubbing saturated oral foam application of chlorhexidine 0/2% 10ml on gum, mucosa, teeth, hard palate, every 12 ho
In intervention group, oral care protocol include, suction, oral assessment, brushing and rubbing saturated oral foam application of chlorhexidine 2% 10ml on gum, mucosa, teeth, hard palate, every 12
Sponsors
Vice chancellor for research of Shiraz University of Medical Science
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Inclusion criteria: 18 years and older; informed consent; patients intubated and who on mechanical ventilation within 48 hours of admission; without a clinical diagnosis of pneumonia at the time of admission ; not to be pregnant ; without significant oral, facial trauma; not to readmitted to the ICU ; without known hypersensitivity to chlorhexidine; without an immunosuppression (disease or drug induced, e.g. organ transplant patient or those on long term steroid therapy); not to hospitalized for burn injury. Exclusion criteria: aspiration; a diagnosed thrombocytopenia (platelet less than 40000); INR above 2 or other coagulopathy.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Oropharyngeal colonization. Timepoint: before intervention and if had exclusion criteria. Method of measurement: send culture and report semiquantitative. | — |
Secondary
| Measure | Time frame |
|---|---|
| Ventilator associated pneumonia. Timepoint: before, during and until 48hours and if had exclusion criteria. Method of measurement: clinical pulmonary infection score and clinical diagnose and start new antibiotic by intensivist. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactLeila Zahed
Shiraz University of Medical Sciences-Fatemeh (PBUH) School of Nursing & Midwifery
Outcome results
None listed