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Comparison of Articaine and Lidocaine as an anesthetic supplemental injection

The comparison of anesthetic efficacy of Articaine versus Lidocaine in Inferior Alveolar Nerve Block plus Intraligamentary injections in mandibular molar teeth with irreversible pulpitis

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015100523253N2
Enrollment
64
Registered
2016-10-17
Start date
2015-09-23
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Irreversible pulpitis. Streptococcus and staphylococcus as the cause of diseases classified to other chapters

Interventions

Intervention 1: After Inferior Alveolar Nerve Block injection with Lidocaine with Epinephrine 1/80000, supplemental Intraligamentry injection with the same anesthetic material will be done. Interventi

Sponsors

Shahid Beheshti University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Patients older than 18 without any systemic diseases; First or second mandibular molar with irreversible pulpitis; No periapical lesion in radiography; Response to Electrical Pulp Tester; Prolonged response to the cold test

Exclusion criteria

Exclusion criteria: Allergic response to Lidocaine or Articaine; pre apical radiolucency; Lactate or pregnant women; Using analgesic drugs since 12 hours before the treatment; Mobility more than 0.5 mm; Probing more than 3 mm in mesial and distal; Severe dental pain that needs emergency treatment; Nonvital coronal pulp tissue; Teeth with full crown; No lip numbness after the Inferior Alveolar Nerve Block injection; No pulp exposure after removing caries

Design outcomes

Primary

MeasureTime frame
Anesthesia. Timepoint: After Inferior Alveolar Nerve Block injection; After supplemental injection. Method of measurement: Electrical pulp tester.;Pulse. Timepoint: Before Inferior Alveolar Nerve Block injection; After Inferior Alveolar Nerve Block injection; After supplemtal injection. Method of measurement: Pulse-oximeter.;Pain during injection. Timepoint: During Inferior Alveolar Nerve Block and supplemental injection. Method of measurement: Heft Parker Visual Analog Scale.;Pain. Timepoint: After Inferior Alveolar Nerve Block and supplemental injection. Method of measurement: Heft Parker Visual Analog Scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNazanin Zargar

Shahid Beheshti University of Medical Sciences

nzargar48@yahoo.com+98 21 2217 5350

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026