cerebrovascular accident ischemic. Cerebrovascular accident NOS
Conditions
Interventions
Intervention 1: Intervention group 1: Infusion 500 cc intralipid during 12 hours per day for 7 days. Intervention 2: Intervention group 3: Prescription 10 cc L-Carnitine per day for 7 days and infusio
Treatment - Drugs
Treatment - Other
Intervention group 1: Infusion 500 cc intralipid during 12 hours per day for 7 days
Intervention group 3: Prescription 10 cc L-Carnitine per day for 7 days and infusion 500 cc intralipid during 12 hours per day for 7 days
Intervention group 2: Prescription 10 cc L-Carnitine per day for 7 days
Control group: Without intervention by L-Carnitine and intralipid
Sponsors
Vice chancellor for research, Mazandaran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
21 Years to 75 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: CVA ischemic MCA inpatient, admitted during first 24 hours after the onset of symptoms, 21-75 years old Exclusion criteria: less than 21years old and more than 75 years old, hepatic failure( rise hepatic enzymes >5nl, cirrhosis), treatment by valproate, treatment by hemodialysis, sepsis, ARDS, triglyceride > 400, acute pancreatitis plus hyperlipidemia, plt < 70000, signs and symptoms appearance more than 72 hours before admission, CNS infections, seizure, migraine.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Neuron specific enolase: NSE. Timepoint: base, 24hr after admission, 48hr after admission, 7th days after admission. Method of measurement: 5 cc serum plasma.;S100B. Timepoint: base, 24hr after admission, 48hr after admission, 7th days after admission. Method of measurement: 5 cc serum plasma.;Lactate dehydrogenase. Timepoint: base, 24hr after admission, 48hr after admission, 7th days after admission. Method of measurement: 5 cc serum plasma.;Pirovate dehydrogenase. Timepoint: base, 24hr after admission, 48hr after admission, 7th days after admission. Method of measurement: 5 cc serum plasma. | — |
Secondary
| Measure | Time frame |
|---|---|
| Evaluation neurologic outcomes : Neurologic examination of GCS, cranial nerves, motor nerves, sensory nerves. Timepoint: At admission time and when Discharge from hospital. Method of measurement: Physical examination. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Shahram Ala
Mazandaran University Of Medical Sciences
Outcome results
None listed