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The effect of morphine sulfate vs. fentanyl in pain management

Comparison of morphine sulfate vs. fentanyl in pain management of ischemic type chest pain in the emergency department

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20151003024317N4
Enrollment
100
Registered
2019-01-05
Start date
2019-01-20
Completion date
Unknown
Last updated
2019-01-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ischemic chest pain. Angina pectoris, unspecified

Interventions

Intervention 1: Control group: patients under 75 years old and more than 50 kg, 5 mg intravenous morphine every 5 minutes if required up to a maximum of 4 doses, and for patients over 75 years old or

Sponsors

Iran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Ischemic chest pain that is not recovered by oxygen, aspirin, and 3 sublingual nitroglycerin receptors Initial systolic blood pressure above 100 mmHg Initial oxygen saturation above 95%

Exclusion criteria

Exclusion criteria: Patients under the eighteen years old Pregnancy Sensitivity to morphine or fentanyl Traumatic injury Cognitive impairment

Design outcomes

Primary

MeasureTime frame
Severity of pain after prescribing. Timepoint: After 2, 6, 10 and 15 minutes after using the drug. Method of measurement: From 1 to 10 (Based on numerical scale).;Blood pressure. Timepoint: After 2, 6, 10 and 15 minutes after using the drug. Method of measurement: Based on the information in the patient file.;Heart rate. Timepoint: After 2, 6, 10 and 15 minutes after using the drug. Method of measurement: Based on the information in the patient file.;Respiratory rate. Timepoint: After 2, 6, 10 and 15 minutes after using the drug. Method of measurement: Based on the information in the patient file.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactArman Zamani Renani

Iran University of Medical Sciences

dr.armanzamani@gmail.com+98 86112348

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026