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Evaluation of the effect of nebulised Furosemide on acute dyspnea

comparison of effects of nebulised Furosemide, oxygen and placebo in patients with acute dyspnea transmited to hospitals by EMS

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20151003024317N12
Enrollment
300
Registered
2020-11-10
Start date
2020-11-21
Completion date
Unknown
Last updated
2020-11-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute dyspnea. Dyspnea

Interventions

Intervention 1: Intervention group 1: In addition to routine treatment, 40 mg of inhaled furosemide will be given as a nebulizer at the scene. Intervention 2: Intervention group 2: In addition to rout

Sponsors

Iran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Acute dyspnea Patient transfer by pre-hospital emergency patients over 18 years old

Exclusion criteria

Exclusion criteria: patients over 75 years old Patients require mechanical ventilation Loss of consciousness Accompanied by another disease that requires treatment in the first 10 minutes of treatment with digoxin, beta-blocker, beta-agonist and calcium blocker Need another inhalation treatment in the first 10 minutes Need non-invasive positive pressure ventilation

Design outcomes

Primary

MeasureTime frame
Acute dyspnea. Timepoint: Before intervention, thirty minutes after intervention. Method of measurement: Shortness of breath chart.;Percentage of oxygen saturation. Timepoint: Before intervention, thirty minutes after intervention. Method of measurement: Percentage of oxygen saturation.

Secondary

MeasureTime frame
Heart rate. Timepoint: Before intervention, thirty minutes after intervention. Method of measurement: Based on the information recorded in patient's record.;Number of breaths. Timepoint: Before intervention, thirty minutes after intervention. Method of measurement: Based on the information recorded in patient's record.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactBabak Mahshidfar

Iran University of Medical Sciences

mahshidfar.b@iums.ac.ir+98 21 6435 2190

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026