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The effects of herbal mixture in infertile women with Polycystic ovary syndrome (PCOS): a randomized controlled trial

Comparison of the efficacy of herbal medicine (Mixture) ? with Clomiphene citrate in treatment of Poly-cystic ovary syndrome (PCOS) and fertility rate in infertile women referring toTabriz Al-Zahra hospital.

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT201509295563N7
Enrollment
102
Registered
2016-01-09
Start date
2015-10-23
Completion date
Unknown
Last updated
2020-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Female infertility. Female infertility associated with anovulation

Interventions

Intervention 1: " :Intervention group: " herbal medicine (Mixture) 700 mgs/day continuous for 3 cycles. Intervention 2: "Control group" Clomiphene Citrate 50-150 mg for 3 cycles. Intervention 3: '' :I

Sponsors

Vice chancellor for Research,Tabriz University Of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 35 Years

Inclusion criteria

Inclusion criteria: willing to participate in the study having at least two out of three of the Rotterdam criteria (2003) for the diagnosis of PCOS aged between 18–35 years old having body mass index (BMI) less than 30 not receiving any treatment at least in the last 3 months (wash out)

Exclusion criteria

Exclusion criteria: patients with diabetes mellitus use of medications such as those helping ovulation or insulin sensitizers thyroid disorders cholesterol-lowering drugs smoking hypertension cardiovascular diseases Cushing syndrome allergy to Mentha spicata (spearmint), Zingiber officinale (ginger) ,Cinnamomum zeylanicum (cinnamon), and Citrus Sinensis (sweet orange)

Design outcomes

Primary

MeasureTime frame
Treatment of ovarian cysts. Timepoint: Before the intervention, three months after intervention. Method of measurement: Ultrasound of the ovaries (ovarian size, number and size of follicles).

Secondary

MeasureTime frame
Pregnancy. Timepoint: 3 months after taking medicinal plants (Citro Plus). Method of measurement: Positive BhcG.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactArash Khaki

PMC Pharmaceutical International Company

arashkhaki@yahoo.com+98 41 3555 6943

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026