Skip to content

Comparison of nerve blocks and epidural anesthesia on stress response in patients undergoing general anesthesia

Comparison of the efficacy of TAP Block and Epidural A. on post operative stress response of elective laparoscopic cholecystectomy surgery in shariati hospital -1393

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015092924268N1
Enrollment
52
Registered
2015-12-07
Start date
2015-12-06
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

General Anesthesia. Intravenous Anesthetics, Other and Unspecified General Anesthetic, Local Anesthetics

Interventions

Intervention 1: At the beginning of surgery before anesthesia induction, TAP BLOCK performed by the Professor of Anesthesiology and with the method of Ultrasound guided Transversus Abdominus plane blo
Prevention
At the beginning of surgery before anesthesia induction, TAP BLOCK performed by the Professor of Anesthesiology and with the method of Ultrasound guided Transversus Abdominus plane block with 20 cc Bu
Initially with 2cc lidocaine 2%, local anesthesia were created then through the number 18 epidural needle inserted into the epidural space then made sure of the correct position of epidural space, 25

Sponsors

Vice Chancellor For Research of Tehran Medical School, Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
17 Years to 49 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Age 18-50 years; BMI<30; Stage 1 and 2 ASA; Surgery time less than 2 hours; Absence of systemic disease such as (heart or lung disease and serious liver-Kidney disease); Absence of contraindications to epidural anesthesia (coagulopathies, infection at needle insertion site, The patient's lack of cooperation, Absence of consent); Absence of any contraindications to perform Block; Absence of a history of immunosuppressive and corticosteroid drugs; Absence of a history of drug addiction and smoking. Exclusion criteria: Failing to block; Incidence of complications during surgery and laparotomy for any reason; Prolongation of operation (more than 2 hours)

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Objective success rate of blockage for anesthesia by injection and deposition of sediment material (Marcaine) between the layers of muscle (IOM and TAM). Timepoint: During of surgery. Method of measurement: Ultrasound sonography.;The Subjective Success Rate of Block. Timepoint: 30 minute. Method of measurement: Check the skin sensation of the same area of block in the epigastric and umbilical and groin.;Pain. Timepoint: Immediately, 6, 12, 24 hours after discharge from recovery. Method of measurement: Visualized Analogue Scale.

Secondary

MeasureTime frame
Blood Sugar ,WBC , CRP , Cortisol, TNF-a and IL-1 level of serum. Timepoint: Before induction of anesthesia and 6 and 24 hours after extubation of patient. Method of measurement: Blood Exam.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactPiroozeh Taheri

Anesthesiology Department, Dr Shariati Hospital, Tehran University of Medical Sciences, Tehran

ven_17@yahoo.com+98 21 8822 0032

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026