General Anesthesia. Intravenous Anesthetics, Other and Unspecified General Anesthetic, Local Anesthetics
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Inclusion criteria: Age 18-50 years; BMI<30; Stage 1 and 2 ASA; Surgery time less than 2 hours; Absence of systemic disease such as (heart or lung disease and serious liver-Kidney disease); Absence of contraindications to epidural anesthesia (coagulopathies, infection at needle insertion site, The patient's lack of cooperation, Absence of consent); Absence of any contraindications to perform Block; Absence of a history of immunosuppressive and corticosteroid drugs; Absence of a history of drug addiction and smoking. Exclusion criteria: Failing to block; Incidence of complications during surgery and laparotomy for any reason; Prolongation of operation (more than 2 hours)
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Objective success rate of blockage for anesthesia by injection and deposition of sediment material (Marcaine) between the layers of muscle (IOM and TAM). Timepoint: During of surgery. Method of measurement: Ultrasound sonography.;The Subjective Success Rate of Block. Timepoint: 30 minute. Method of measurement: Check the skin sensation of the same area of block in the epigastric and umbilical and groin.;Pain. Timepoint: Immediately, 6, 12, 24 hours after discharge from recovery. Method of measurement: Visualized Analogue Scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood Sugar ,WBC , CRP , Cortisol, TNF-a and IL-1 level of serum. Timepoint: Before induction of anesthesia and 6 and 24 hours after extubation of patient. Method of measurement: Blood Exam. | — |
Countries
Iran (Islamic Republic of)
Contacts
Anesthesiology Department, Dr Shariati Hospital, Tehran University of Medical Sciences, Tehran