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Comparing the effects of intravenous ephedrine, of muscular ephedrine and of intradermal ephedrine in preventing hypotension

Comparing the effects of intravenous ephedrine, of muscular ephedrine and of intradermal ephedrine in preventing hypotension in caesarean section patients with spinal anesthesia

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015092824233N1
Enrollment
96
Registered
2016-01-30
Start date
2015-05-15
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypotension induced by injection of intravenous ephedrine, of muscular ephedrine and of intradermal ephedrine. Hypotension due to drugs

Interventions

Intervention 1: In The third group received an intravenous drug, Immediately after the entry of women into the operating room 10 milliliters per kilogram of body weight Ringer will be administered thr
Treatment - Drugs
Placebo
In The third group received an intravenous drug, Immediately after the entry of women into the operating room 10 milliliters per kilogram of body weight Ringer will be administered through IV No. 18 f
In The fourth group received a placebo, Immediately after the entry of women into the operating room 10 milliliters per kilogram of body weight Ringer will be administered through IV No. 18 for them.
In the second group received intradermal drug, Immediately after the entry of women into the operating room 10 milliliters per kilogram of body weight Ringer will be administered through IV No. 18 for
The first group received the drug muscle, Immediately after the entry of women into the operating room 10 milliliters per kilogram of body weight Ringer will be administered through IV No. 18 for them

Sponsors

Vice chancellor for research, Jahrom University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 30 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: 20 to 30years old mothers who participate in class 1 and 2 ASA; tend to have spinal anesthesia; do not have a base systolic blood pressure more than 130 mmHg and less than 90 mmHg; do not have a history of high blood pressure and are consciously willing to participate in the project. Exclusion criteria: participants in class 3 and 4 ASA; patients with cardiovascular disease; people with tachycardia (over 100 beats per minute) and with bradycardia (less than 60 beats per minute); any history of hypertension, diabetes mellitus; patients with thyroid disease, using beta-agonists and beta blockers; preterm delivery; using banned drugs during pregnancy; preeclampsia and pre-eclampsia and eclampsia.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Blood pressure. Timepoint: Every 2.5 minutes to 10 minutes and then until 45 minutes every 5 minutes. Method of measurement: mmHg.

Secondary

MeasureTime frame
Nausea and vomiting. Timepoint: every 15 minutes. Method of measurement: Scale Alderet.;Shivering. Timepoint: Every 15 minutes. Method of measurement: Scale rossely & mahajan.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohsen Farkhondehfal

Jahrom University of Medical Sciences

Mohsen.farkhondehfal@gmail.com+98 71 3840 7325

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026