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New protocol in assisted reproductive techniques in patients with polycystic ovarian syndrome

Evaluation of pretreatment with Cetrotide in antagonist protocol in patients with PCOS in ART cycles.

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT201509276420N14
Enrollment
100
Registered
2015-10-29
Start date
2015-03-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility. Complication associated with artificial fertilization, unspecified

Interventions

Intervention 1: In control group (50 patients) from 2th cycle gonadotropin injected. When dominant follicle reached to 12-13 mm, cetrotide injected and when dominant follicle reached to 17 mm , trigge
Treatment - Drugs
In control group (50 patients) from 2th cycle gonadotropin injected. When dominant follicle reached to 12-13 mm, cetrotide injected and when dominant follicle reached to 17 mm , triggering was done an
In intervention group (50 patients) in cycle 2-4 day, GnRh- antagonist (cetrotide) injected and then from 5th cycle gonadotropin injected. When dominant follicle reached to 12-13 mm, cetrotide again i

Sponsors

Research and Clinical Center for Infertility,Shahid Sadoughi University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: infertile PCOS patients which are candidate for ART. Exclusion criteria: women older than 40 years; history of endocrine disorder; intrauterine abnormality (uterine polyp & sub mucosal fibroma & intrauterine adhesions); severe endometriosis; and azoospermia of partner.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Number of oocytes and embryos. Timepoint: Puncture and transfer day. Method of measurement: number.

Secondary

MeasureTime frame
Chemical and clinical pregnancy. Timepoint: 14 days after transfer & 3 weeks after positive B-HCG. Method of measurement: B-HCG test & vaginal ultrasonography.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr maryam eftekhar

Sadoughi University of Medical Sciences ,Yazd

eftekharmaryam@yahoo.com+98 35 3824 7085

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026