Effect of Apium Graveolence and Trachyspermum Copticum traditional product on clinical symptoms of patients with Functional Dyspepsia

Clinical trial of compared of Apium Graveolence and Trachyspermum Copticum traditional product effect with placebo and omeprazol on clinical symptoms of 18 to 60 years old patients with Functional Dyspepsia

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2015092724228N1

Enrollment

150

Registered

2016-06-03

Start date

2015-12-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Functional Dyspepsia. Indigestion

Interventions

Intervention 1: Apium Graveolense beans 250 mg plus Trachyspermum Copticum beans 250 mg, two times daily,after meal. Intervention 2: Corn starch 500 mg, two times daily, after meal. Intervention 3: Om

Treatment - Drugs

Placebo

Apium Graveolense beans 250 mg plus Trachyspermum Copticum beans 250 mg, two times daily,after meal

Corn starch 500 mg, two times daily, after meal

Omeprazol 20 mg, daily

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria are 18 to 60 year-old patients with Functional Dyspepsia, without organic disorders on physical examination and endoscopy Exclusion criteria are Pregnancy and Lactation; History of convulsion; Active UTI; Use of chemical and herbal drugs of functional dyspepsia; use of anticoagulant drug;serious diseases like diabetes and cardiovascular diseases, Esophagus and gastrointestinal surgery, severe mental retardation, drug abuse, patient’s unwillingness to continue the project, not filling out the consent form History of peptic ulcer or reflux disease; Alarm sign (Weight loss, Anemia, Bloody stool, Dysphagia,etc

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Severity assessment of dyspepsia. Timepoint: During 8 weeks follow up study. Method of measurement: The gastrointestinal symptom scale.;Quality of life. Timepoint: At baseline, 2, 4, 8 weeks. Method of measurement: NDI10 quality of life scale.	—

Secondary

Measure	Time frame
Side effects. Timepoint: During 12 weeks follow up study. Method of measurement: Questionnair.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAzimidehali Maryam

Kerman University of Medical Science

m_azimidehali@collegian.kmu.ac.ir, dr.azimm@gmail.com+98 34 3312 2050

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026