Ulcerative colitis. Ulcerative colitis
Conditions
Interventions
Intervention 1: Intervention group: consumes 2 capsules daily contain two parts of Plantago major extract, and one part of Rheum khorasanicum prepared by the pharmacist in the pharmaceutical laborator
Sponsors
Kerman University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Patients aged 18 to 60 with mild and moderate ulcerative colitis confirmed by endoscopy and biopsy and diagnosed by a gastroenterologist who signed the informed consent form and did not meet the exclusion criteria.
Exclusion criteria
Exclusion criteria: Pregnancy or breastfeeding Taking antibiotics Taking herbal medicines, NSAIDs, OCPs or hormone therapy (in the last 2 weeks) Complications of the disease (such as massive bleeding requiring hospitalization or emergency surgery, fulminant colitis, peritonitis, toxic megacolon, obstructive stenosis), Suffering from liver, kidney, heart, cancer or celiac disease at the same time Addiction to smoking or drugs Suffering from other autoimmune diseases
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Partial Mayo score. Timepoint: At the beginning of the study, 3, 6 and 10 weeks. Method of measurement: Partial Mayo score questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of life. Timepoint: At the beginning of the study, 3, 6 and 10 weeks. Method of measurement: Quality of life questionnaire (IBDQ-9).;Anxiety, stress, and depression. Timepoint: At the beginning of the study, 3, 6 and 10 weeks. Method of measurement: DASS-21 questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMaryam Azimi
Kerman University of Medical Sciences
Outcome results
None listed