Effect of Iranian Traditional Medicine drugs in the treatment of Migraine.

Efficacy of “Etrifel” and “Mastaki” on monthly bouts of headache in Migraineurs with Gastric Headache.

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT2015092324150N1

Enrollment

Registered

2017-01-08

Start date

2017-01-04

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Migraine. Migraine

Interventions

Etrifel confection, 10 grams(or maximum tolerated dose), once daily for 12 weeks, orally, before breakfast. Mastic gum powder, 3 grams(or maximum tolerated dose), once daily for 12 weeks, orally, befo

Treatment - Drugs

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Male or female 18-65 years old; diagnosed since 6 months ago with Episodic or Probable Migraine ± aura by a specialist according to criteria from ICHD-III; having 3 to 14 attacks of migraine in a month from 3 months ago; diagnosed with Gastric Headache according to Iranian Traditional Medicine Questionnaire; normal neurologic examination Exclusion criteria: Taking preventive drugs in the last 3 months; history of drug abuse; history of allergy to the trial drugs; pregnant or breast feeding women; systemic and other neurologic diseases

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Headache frequency in a period of 4 weeks. Timepoint: before intervention, 4, 8, and 12 weeks after the start of intervention. Method of measurement: Questionnaire.	—

Secondary

Measure	Time frame
Headache severity. Timepoint: before intervention, 4, 8, and 12 weeks after the start of intervention. Method of measurement: Visual Analgue Scale.;Headache duration. Timepoint: before intervention, 4, 8, and 12 weeks after the start of intervention. Method of measurement: Questionnaire.;The amount of rescue medication use in each attack. Timepoint: before intervention, 4, 8, and 12 weeks after the start of intervention. Method of measurement: Questionnaire.	—

Measure

Time frame

Headache severity. Timepoint: before intervention, 4, 8, and 12 weeks after the start of intervention. Method of measurement: Visual Analgue Scale.;Headache duration. Timepoint: before intervention, 4, 8, and 12 weeks after the start of intervention. Method of measurement: Questionnaire.;The amount of rescue medication use in each attack. Timepoint: before intervention, 4, 8, and 12 weeks after the start of intervention. Method of measurement: Questionnaire.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMajid Talafi Noghani

Iranian Traditional Medicine Department, Shahed university

M.Noghani@Shahed.ac.ir+98 21 5121 4055

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026