Acute attack asthma. Asthma
Conditions
Interventions
Intervention 1: Intervention Group: (N Salbutamol 2.5 mg + N Ipratropium 0.5 mg ) *3 times every 20 min. + 2 tabulate Montolocast 5 mg at 0 min. chew. Intervention 2: Control Group: (N Salbutamol 2.
Treatment - Drugs
Placebo
Intervention Group: (N Salbutamol 2.5 mg + N Ipratropium 0.5 mg ) *3 times every 20 min. + 2 tabulate Montolocast 5 mg at 0 min. chew.
Control Group: (N Salbutamol 2.5 mg + N Ipratropium 0.5 mg ) *3 times every 20 min. + 2 tabulate Placebo 5 mg at 0 min. chew.Total Patient at 0, 30, 60, 90,150min. After starting the intervention th
Sponsors
Vice chanceller for research, Ahvaz Jundishapur University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Inclusion criteria: age above 18 years old; documented asthmatic patients with spiropmetry. Exclusion criteria: no response to therapy; use of epinephrine or MgSO4 or IPPV during treatment; patient refuse from continue of treament; lung diseases like ILD; cigarrete smoking.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical state. Timepoint: Before intervention, 30, 60, 90, 150 minutes after intervention. Method of measurement: Base on alert status, talking, wizing, use of respiratory mu.;Forced Expiratory Volum in First Secend (FEV1). Timepoint: Before intervention, 30, 60, 90, 150 minutes after intervention. Method of measurement: Mililiter with use of Peak Flow Meter.;Peak Expiratory Flow Rate(PEFR). Timepoint: Before intervention, 30, 60, 90, 150 minutes after intervention. Method of measurement: Mililiter with use of Peak Flow Meter. | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood pressure. Timepoint: Before intervention, 30, 60, 90, 150 minutes after intervention. Method of measurement: mmHg.;Pulse Rate. Timepoint: Before intervention, 30, 60, 90, 150 minutes after intervention. Method of measurement: Rate/Minutes.;Respiratory Rate. Timepoint: Before intervention, 30, 60, 90, 150 minutes after intervention. Method of measurement: Rate/Minutes.;Saturation of arterial blood oxygen (SO2 %). Timepoint: Before intervention, 30, 60, 90, 150minutes after intervention. Method of measurement: Pulse Oximetry.;Pulsus Paradox. Timepoint: Before intervention, 30, 60, 90, 150 minutes after intervention. Method of measurement: 10 mmHg reduction of blood pressure during inspiration. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Hasan Motamed
Ahvaz Golestan Hospital
Outcome results
None listed