The effect of 3% hypertonic saline and salbutamol in treatment of patients with acute bronchiolitis

The effectiveness and non-effectiveness of saline 3% and salbutamol in the treatment of patients with acute bronchiolitis

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2015092214333N39

Enrollment

Registered

2015-11-03

Start date

2015-02-04

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute bronchiolitis. Acute bronchiolitis

Interventions

Intervention 1: Control group just 15/0 mg / kg Salbutamol will given every 8 hours. Intervention 2: Experimental group, 4 ml Lytrsalyn hypertonic 3% plus15/0 mg/kg salbutamol every 8 hours will give

Treatment - Drugs

Control group just 15/0 mg / kg Salbutamol will given every 8 hours

Experimental group, 4 ml Lytrsalyn hypertonic 3% plus15/0 mg/kg salbutamol every 8 hours will given by nurse

Eligibility

Sex/Gender

All

Age

1 Months to 2 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: children under 2 years old; children with acute bronchiolitis. Exclusion criteria: children with cystic fibrosis; bronchopulmonary dysplasia and those with heart disease; premature babies with GA=34; patients who had used steroids during the last 48 hours prior to admission; children with immunodeficiency.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Chest auscultation in terms of wheezing. Timepoint: Beginning and end of study. Method of measurement: By a doctor.;Cough. Timepoint: Beginning and end of study. Method of measurement: By doctor and counting.;Respiratory rate. Timepoint: Beginning and end of study. Method of measurement: By doctor and counting.;Blood oxygen saturation. Timepoint: Beginning and end of study. Method of measurement: By pulse oximeter.;Lung retraction. Timepoint: Beginning and end of study. Method of measurement: Based on physician observation.;The temperature of patient. Timepoint: Beginning and end of study. Method of measurement: Thermometer device.;Overall health of Patient. Timepoint: Beginning and end of study. Method of measurement: Based on physician observation and patient interview.;The severity of bronchiolitis. Timepoint: Beginning and end of study. Method of measurement: Based on the observations and examined by a doctor.	—

Measure

Time frame

Chest auscultation in terms of wheezing. Timepoint: Beginning and end of study. Method of measurement: By a doctor.;Cough. Timepoint: Beginning and end of study. Method of measurement: By doctor and counting.;Respiratory rate. Timepoint: Beginning and end of study. Method of measurement: By doctor and counting.;Blood oxygen saturation. Timepoint: Beginning and end of study. Method of measurement: By pulse oximeter.;Lung retraction. Timepoint: Beginning and end of study. Method of measurement: Based on physician observation.;The temperature of patient. Timepoint: Beginning and end of study. Method of measurement: Thermometer device.;Overall health of Patient. Timepoint: Beginning and end of study. Method of measurement: Based on physician observation and patient interview.;The severity of bronchiolitis. Timepoint: Beginning and end of study. Method of measurement: Based on the observations and examined by a doctor.

—

Countries

Iran (Islamic Republic of)

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026