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Comparison medicinal doses of midazolam in sedation of children under 2 years for brain CT scan

Comparison of the sedative effect of two different doses of midazolam, 0.1mg/kg and 0.3mg/kg for brain CT-scan in children aged under 2 old years

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015092121289N2
Enrollment
120
Registered
2015-11-01
Start date
2015-03-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sedation of children for CT scan. General medical examination, Routine child health examination

Interventions

Intervention 1: Patients in the first group a dose of 0.1 mg / kg intravenous midazolam were injected during the study, children at a dose of midazolam 0.1mg / kg and 0.3mg / kg for them, was not suf
Treatment - Drugs
Patients in the first group a dose of 0.1 mg / kg intravenous midazolam were injected during the study, children at a dose of midazolam 0.1mg / kg and 0.3mg / kg for them, was not sufficient to perfo
Patients in the second group, a dose of 0.3 mg / kg intravenous midazolam were injected during the study, children at a dose of midazolam 0.1mg / kg and 0.3mg / kg for them, was not sufficient to perf

Sponsors

research deputy of Ahvaz Jundishapur University of Medical Sciences Faculty of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
1 Days to 2 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Children under 2 years old; suffered from head trauma; and have permission to do brain CT scan. Exclusion criteria include anticipated difficult airway; history of adverse reactions to benzodiazepines; hemodynamic instability; congestive heart failure; liver disease; impaired level of consciousness (defined as a Glasgow coma scale less than 15); uncontrolled vomiting; gastric esophageal reflux history; concomitant use of drugs and uremia.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Ramsay sedation score (RSS). Timepoint: Initiation of intervention. Method of measurement: Ramsay sedation score (RSS).

Secondary

MeasureTime frame
Duration and impact of sedation medication. Timepoint: first day. Method of measurement: Monitor and measure.;Oxygen saturation. Timepoint: first day. Method of measurement: Measurement of arterial blood gases.;Respiratory and pulse rate. Timepoint: first day. Method of measurement: Monitor and measure.;Complications. Timepoint: The first day until the seventh day. Method of measurement: Monitor and measure.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHasan Barzegar

Ahvaz Jundishapur University of Medical Sciences Faculty of Medicine

h-b1979@yahoo.com+98 61 3161

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026