Female infertility. Female infertility
Conditions
Interventions
Intervention 1: Daily injection of 100 unit rFSH (Gonal-f) subcutaneously. Intervention 2: Single dose injection of 100 micrograms per 0.5 ml Solution of FSH-CTP (Corifollitropin) subcutaneously.
Treatment - Drugs
Daily injection of 100 unit rFSH (Gonal-f) subcutaneously
Single dose injection of 100 micrograms per 0.5 ml Solution of FSH-CTP (Corifollitropin) subcutaneously
Sponsors
Vice Chancellor for Research, Guilan University of Medical Sciences, Rasht, Iran
Eligibility
Sex/Gender
Female
Age
18 Years to 36 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Age 18 to 36 years; Regular spontaneous menstrual periods (cycles 24-35 days); BMI 19 to 25; There are both ovaries; No problems with the uterus or ovaries on ultrasound or scan 6 weeks ago; Hysterosalpingography or Laparoscopy with the natural structure of the uterus during the last 2 years; 2-4 period day FSH less than 10; Normal TSH; Acceptable Analysis of sperm for ICSI in the past 6 months Exclusion criteria: Patients who require a higher dose of 150 IU FSH per day; Patients who have more than 10-12 follicles under 10mm in Ultrasound screening on day 2-3 of period; 2-3 previous ART cycles with poor response to gonadotropins and inappropriate recovered oocytes; 3 or more previous failed ART; A lack of fertilization in previous ICSI; History of previous ICSI where there is plenty of motile sperm (taking sperm from the testis and epididymis); Endometriosis III and IV Background; There are one-sided or double-sided hydrosalpinx; Any underlying disease (liver, thyroid and kidney); Smoking
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The success of Pregnancy. Timepoint: 14 days after ICSI and week 7 of Pregnancy. Method of measurement: Number of pregnancy confirmed by serum ß-hCG 14 days after ICSI and recognizing fetal heart rate in trans-vaginal ultrasound divided by the number of people in each of the two groups. | — |
Secondary
| Measure | Time frame |
|---|---|
| Ovarian hyperstimulation syndrome. Timepoint: During ovulation stimulation. Method of measurement: According examination.;The incidence of multiple pregnancy. Timepoint: From fifth week of pregnancy. Method of measurement: According ultrasound. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr ziba zahiri
Guilan University of Medical Sciences
Outcome results
None listed