Post partum depression. Mental and behavioural disorders associated with the puerperium, not elsewhere classified
Conditions
Interventions
Intervention 1: Capsule fluoxetine 20 to 40mg/day as icontrol group for 6 weeks. Intervention 2: Capsule saffron 15mg BID as intervention group for 6 weeks.
Treatment - Drugs
Capsule fluoxetine 20 to 40mg/day as icontrol group for 6 weeks
Capsule saffron 15mg BID as intervention group for 6 weeks
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Presence of Major Depressive Disorder; with peripartum onset based on DSM-5 criteria; age between 18 to 45 years old; score lower than 18 in Hamilton Rating Scale for depression. Exclusion criteria: -Psychotic symptoms or any other major psychiatric disorder; receiving any antidepressants during past one month or ECT during past two months; Presence of hypothyroidism or hyperthyrodism; srious suicidality or infanticide ideas; substance abuse or dependence uring the last three months
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of depression. Timepoint: Baseline and weeks 2-4-6 after beginig of treatment. Method of measurement: by Hamiltion Depression Rating Scale 17-Item. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactProf. Shahin Akhondzadeh
Tehran University of Medical Sciences
Outcome results
None listed