The effect of oral consumption of sesame oil on patients with type 2 diabetes

The effect of oral consumption of sesame oil on anthropometric, metabolic and oxidative stress markers of patients with type 2 diabetes

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20150920024103N2

Enrollment

Registered

2020-07-04

Start date

2020-07-25

Completion date

Unknown

Last updated

2020-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetes type 2. Type 2 diabetes mellitus

Interventions

Intervention 1: Intervention group: oral consumption of sesame oil, 15 gram/day during 8 weeks. Intervention 2: Control group: oral consumption of sunflower oil , 15 gram/day during 8 weeks.

Eligibility

Sex/Gender

All

Age

30 Years to 70 Years

Inclusion criteria

Inclusion criteria: Participants must be patients of type 2 diabetes and their diabetes have diagnosed at least 2 years ago ( FBG =125 mg/dl, (OGTT) =200 mg/dl, HbA1C =7 and blood sugar =200 mg/dl) Have nearly similar economic and social situation Have no change in anti-diabetic medication since at least 4 weeks before the start of clinical trial Have HGA1C higher than 7% and lower than 9% Patients must be similar in anti-diabetic and statin drugs Patients should not be smoking and alcohol consumer

Exclusion criteria

Exclusion criteria: Patients show the allergic reaction during the intervention Medication changes or treatment shift to insulin Significant change in physical activities Hyperthyroidism or hyperthyroidism Pregnancy or lactation Omega 3 Supplement consumption Patients suffer from any type of inflammation, organs failure, Corticosteroids consumption and GFR rate under 30

Design outcomes

Primary

Measure	Time frame
Anthropometric measurements. Timepoint: Before and after intervention. Method of measurement: Height meters and weighing Scale.;Fasting blood sugar. Timepoint: Before and after intervention. Method of measurement: Laboratory kit.;Triglycerides. Timepoint: Before and after intervention. Method of measurement: Enzymatic kit.;High density lipoprotein. Timepoint: Before and after intervention. Method of measurement: Enzymatic kit.;Low density lipoprotein. Timepoint: Before and after intervention. Method of measurement: Enzymatic kit.;Cholesterol. Timepoint: Before and after intervention. Method of measurement: Enzymatic kit.;C-reactive protein. Timepoint: Before and after intervention. Method of measurement: ELISA kit.;Total antioxidant capacity. Timepoint: Before and after intervention. Method of measurement: Spectrophotometry.;GSH. Timepoint: Before and after intervention. Method of measurement: Spectrophotometry.;MDA. Timepoint: Before and after intervention. Method of measurement: Spectrophotometry.	—

Measure

Time frame

Anthropometric measurements. Timepoint: Before and after intervention. Method of measurement: Height meters and weighing Scale.;Fasting blood sugar. Timepoint: Before and after intervention. Method of measurement: Laboratory kit.;Triglycerides. Timepoint: Before and after intervention. Method of measurement: Enzymatic kit.;High density lipoprotein. Timepoint: Before and after intervention. Method of measurement: Enzymatic kit.;Low density lipoprotein. Timepoint: Before and after intervention. Method of measurement: Enzymatic kit.;Cholesterol. Timepoint: Before and after intervention. Method of measurement: Enzymatic kit.;C-reactive protein. Timepoint: Before and after intervention. Method of measurement: ELISA kit.;Total antioxidant capacity. Timepoint: Before and after intervention. Method of measurement: Spectrophotometry.;GSH. Timepoint: Before and after intervention. Method of measurement: Spectrophotometry.;MDA. Timepoint: Before and after intervention. Method of measurement: Spectrophotometry.

—

Secondary

Measure	Time frame
Insulin resistance. Timepoint: before and after intervention. Method of measurement: Elisa Kit.;Insulin sensitivity. Timepoint: Before and after intervention. Method of measurement: Elisa Kit.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSadegh Jafarnejad

Kashan University of Medical Sciences

sjafarnejad@razi.tums.ac.ir+98 31 5554 0021

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026