Atrial fibrillation. Atrial fibrillation and flutter
Conditions
Interventions
Intervention 1: 80 patients are in the supplementation or intervention group. These patients the day before surgery will receive 2 grams of omega-3 as yellow capsules (twice a day), and 1 g of vitami
Prevention
Placebo
80 patients are in the supplementation or intervention group. These patients the day before surgery will receive 2 grams of omega-3 as yellow capsules (twice a day), and 1 g of vitamin C (twice daily
80 patients are in the control or placebo group. These patients the day before surgery will receive 2 grams of placebo omega-3 as yellow capsules (twice a day), and 1 g placebo of vitamin C (twice dai
Sponsors
Vice chancellor for research Lorestan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
30 Years to 90 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Age between 30 and 90 years; patients candidate by physicians for open heart surgery (coronary artery bypass graft, with or without valve surgery) ; having sinus rhythm in ECG before surgery; provide informed written consent; Do not use vitamin supplements containing antioxidants or omega-3 supplements and don't use of fish oil in the last three months ; Now is not pregnant; Known allergy or intolerance fish oil and vitamin C ; comorbidities such as chronic rheumatoid arthritis, malignancy, chronic renal failure, severe liver failure (serum creatinine> 2.0 mg / dL), and recent infection Exclusion criteria: Sensitivity to omega-3 and vitamin C (during studies) or severe gastrointestinal side effects (diarrhea) ; Currently is pregnant ; for a heart transplant or ventricular assist devices are planned ; Now reluctant to provide information and is not satisfied ; use of anti-arrhythmic drugs class 1 and 3 ; congenital heart Diseases ; CPR during or after surgery
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of atrial fibrillation. Timepoint: While intervention. Method of measurement: The number of cases and counting.;Length of stay in the icu, post icu, and the length of stay in hospital. Timepoint: While intervention. Method of measurement: In terms of time.;Fatigue. Timepoint: Before and after the intervention. Method of measurement: Tools mfi-20. | — |
Secondary
| Measure | Time frame |
|---|---|
| Metoral drug. Timepoint: preintervention. Method of measurement: Observation.;Ejection fraction. Timepoint: preintervention. Method of measurement: Observation. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHassan Najafizadeh
Lorestan University of Medical Sciences
Outcome results
None listed