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Effect of Aromatherapy in CIPN and Fatigue

Comparison of the Effectiveness of Aromatherapy-Massage with Classic Massage in Chemotherapy-Induced Neuropathic Pain and Fatigue in Cancer Patients

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20150919024080N19
Enrollment
75
Registered
2021-06-24
Start date
2021-04-21
Completion date
Unknown
Last updated
2021-07-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Drug-induced polyneuropathy. Condition 2: Neoplastic (malignant) related fatigue. Neoplastic (malignant) related fatigue

Interventions

Intervention 1: First Intervention group: In this group, Aromatherapy-Massage is performed using the main combination oil (lavender, chamomile, mint, coconut) prepared by Adonis Goldaroo Company. The
Then the researcher delivers a bottle containing 50 cc of 3% combined essential oil (for the Aromatherapy-Massage group) along with an pamphlet containing image (to explain and show the steps of the m

Sponsors

Khoram-Abad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: The patient should be between 18 and 80 years old Have at least one paraesthesia point (based on NRS) More than 10,000 platelets per cubic millimeter of blood No severe inflammatory lesions, itching or sores on the hands or feet The patient must be in stage II or III cancer Has received at least one session of chemotherapy and is scheduled to receive at least three more sessions within the next month Existence of fatigue resistant to common treatments If a specific cause for fatigue, such as anemia, insomnia, depression, or hypercalcemia, is identified, it should be treated first. No history of peripheral neuropathy for any cause including diabetes mellitus, autoimmune disease, AIDS or previous chemotherapy Patients with the infection are first treated with oral or intravenous antibiotics No known mental illness Ability to communicate and make telephone calls in Persian After standardizing the fatigue score in the range of 0-100 people with a fatigue score above 30 and a pain score of 3 enter the study Patient consent to participate in the study No spread of metastasis to distant and vital organs such as brain and lymph nodes Inclusion criteria for family caregiver: having a spouse or child relationship with the patient, experience of caring and following the patient for at least one month and willingness to participate in the study

Exclusion criteria

Exclusion criteria: Deep vein thrombosis Perform Aromatherapy-Massage for the past month Dose reduction or discontinuation of medications Allergy to lavender, chamomile and mint oils Acute infections require oral or intravenous antibiotics or antiviral and antifungal drugs. Drug therapy during the study to prevent or treat neuropathy Existence of coagulation problems or taking anticoagulants haemorrhage Pregnancy Soft tissue infection Oncological emergencies (such as Tumor Lysis Syndrome) Participate in other rehabilitation programs, meditation and hydrotherapy, etc. while studying Exclusion criteria for family caregiver: change the role of family caregiver and transfer his/her role to other family members during the study

Design outcomes

Primary

MeasureTime frame
Neropathic Pain. Timepoint: Before, 14 and 28 days after the start of the intervention. Method of measurement: DN4 questionnaire.;Fatigue. Timepoint: Before, 14 and 28 days after the start of the intervention. Method of measurement: CFS questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAmirhosein Hasanvand

Khoram-Abad University of Medical Sciences

amir.h1999@yahoo.com+98 66 3321 3501

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026