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Effect of analgesia-sedation protocol on pain, agitation and cardiovascular response of trauma

Effect of analgesia-sedation protocol on pain, agitation and cardiovascular response of trauma patient in the surgical intensive care unit

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20150919024080N17
Enrollment
84
Registered
2020-08-26
Start date
2020-08-22
Completion date
Unknown
Last updated
2020-09-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

trauma. Acute pain due to trauma

Interventions

Intervention 1: Intervention group: In the protocol (intervention) group, first, a comprehensive examination of the patient was performed. After, the patient entered the ward, simultaneously vital sig

Sponsors

Khoram-Abad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 89 Years

Inclusion criteria

Inclusion criteria: Trauma patients (abdominal, chest, orthopedics trauma, and etc.) Patients need a ventilator with a minimum duration of 24 hours connected to the ventilator. Patients separated from the ventilator The minimum duration of separation from the ventilator is 24 hours. Willingness to participate in the study. Being able to self-report pain or express pain behaviors. level of consciousness equal and above 7 The minimum length of hospital stay in the ICU should be 48 hours. No pregnancy. No coagulation disorders

Exclusion criteria

Exclusion criteria: Transfer to home and using palliative care unit (end of life). Plant life, quadriplegia and the need for continuous infusion of nerve blockers and inhaled prostacyclins. Deep sedation to quit alcohol. Need for continuous infusion of sedative or analgesic for more than 24 hours. Patients with permanent brain injury admitted to neurosurgery wards. Deep sedation for treatment of active seizures. Patients in the final stage of kidney and liver failure. Cardiac arrest. Neurovascular injury, burns, ear, nose and throat surgeries, maxillofacial surgery, or plastic surgery to place a flap on the head or neck.

Design outcomes

Primary

MeasureTime frame
Pain intensity in trauma patients in special surgical wards. Timepoint: Twice a day at 8-10 and 18-16 hours for a maximum of 4 days. Method of measurement: Behavioral Pain Scale BPS-NI, BPS, NRS Pain Numerical Scale.;Severity of restlessness in trauma patients in surgical wards. Timepoint: Twice a day at 8-10 and 18-16 hours for a maximum of 4 days. Method of measurement: Richmond Scale (RASS).;Incidence of delirium in trauma patients in special surgical wards. Timepoint: Once a day for 18-16 hours for a maximum of 4 days. Method of measurement: CAM-ICU scale.

Secondary

MeasureTime frame
Cardiovascular response of trauma patients in surgical special wards. Timepoint: Before and after each drug intervention. Method of measurement: Blood pressure with Blood pressure monitor and pulse monitoring with cardiac and respiratory monitoring with manual count in one minute.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaryam Hashemi

Khoram-Abad University of Medical Sciences

maryamhashemi5353@gmail.com+98 66 3331 7759

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026