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Effect of laser in recurrent aphtous ulcers

A comparsion between CO2and Diod laser effect as complementary treatment in recurrent aphtous ulcers in patients:A randomised clinical trial.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015091323992N1
Enrollment
64
Registered
2015-11-22
Start date
2014-04-18
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Recurrent aphthous ulcer. Recurrent aphthous ulcer

Interventions

Intervention 1: group1: 0.5 mg betamethasone tablet In 30 cc of water for Qid. Intervention 2: group3: lidocaine spray(10%) before laser on injury(50ml-Iran)
GaALAs Diode laser
wave length: 808 nm
5 mm from the mucosa
Intensity :1.5 j
Continious mode ( photo lase , Milan – Italy)
0.5 mg betamethasone tablet In 30 cc of water for Qid. Intervention 3: group4: lidocaine spray(10%) before laser on injury(50ml-Iran)
placebo laser
0.5 mg betamethasone tablet In 30 cc of water for Qid. Intervention 4: group2: lidocaine spray(10%) before laser on injury(50ml-Iran)
CO2laser
wave length: 10600 nm
5-8 seconds
5-7 mm from the mucosa
Power :30 Watt
Continious mode General Project S.I.R- Italia)
0.5 mg betamethasone tablet In 30 cc of water for Qid.
Treatment - Other

Sponsors

Research Center of Kerman Dental School
Lead Sponsor

Eligibility

Sex/Gender
All
Age
11 Years to No maximum

Inclusion criteria

Inclusion criteria: The inclusion criteria : a reliable history of minor RAS; the presence of 1-5 numbers of discrete, painful, aphthous ulcers at the same time; enrollment of the patient into the study within 3 days or less of the appearance of the ulcers. The exclusion criteria : age less than 12 years; people with systemic diseases such as liver-kidney-heart immunological problems; pregnancy & breast-feeding; smokers and alcohol; any known systemic disease that could have predisposed the patient to miRAS like Behcet disese, Cowden, Ulcerative Colitis, Severe Anemia; a history of having received corticoid-steroid therapy in the previous 1 months and antibiotic therapy in the 2 weeks ago.;treatment of their current ulcers with any form of topical medications

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Ulcer pain and severity. Timepoint: before intervention-1 day after intervention-4 days after intervention-7 days after intervention. Method of measurement: (VAS) Visual Analogue Scale.;Healing time. Timepoint: before intervention-1 day after intervention-4 days after intervention-7 days after intervention. Method of measurement: day.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactRaziehsadat Rezvaninejad

Kerman Dental School

rezvaninezhad@gmail.com+98 34 3211 9023

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026