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Effect ot Fenugreek in treatment of Acne Vulgaris

Comparison of the efficacy of oral Trigonella foenum-graecum seed extract and oral azithromycin in the severity of acne vulgaris; a randomized controlled clinical trial

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015091123978N1
Enrollment
20
Registered
2017-11-05
Start date
2015-07-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acne vulgaris. Acne vulgaris

Interventions

Intervention 1: Intervention group, in addition to diet and hygienic recommendations, use capsules containing fenugreek hydro alcoholic extract 1g / d for 2 months. Intervention 2: Control group, in a
Treatment - Drugs
Intervention group, in addition to diet and hygienic recommendations, use capsules containing fenugreek hydro alcoholic extract 1g / d for 2 months.
Control group, in addition to diet and hygienic recommendations, use Azithromycin capsules 250mg/d for 2 months.

Sponsors

Shiraz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
12 Years to 30 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: age 12 to 30 years; GAGS score between 1 and 30; signature consent form. Exclusion criteria: previous consumption of oral acne controller medications, such as antibiotics, isotretinoin, oral contraceptive pills; administration of drugs that caused acne such as testosterone, progesterone, steroids, lithium, phenytoin, and isoniazid; patients with symptoms of endocrine disorders especially hyperandrogegism, including polycystic ovarian syndrome (oligomenorrhea, polycystic ovaries, hirsutism), Cushing syndrome (rapid weight gain, buffalo hump, moon face, excess sweating, purple or red striae on the body and hirsutism), CAH, androgen-secreting tumors, and acromegaly; severe skin problem; women who were pregnant or lactating.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Severity of skin lesions. Timepoint: At baseline, 30 and 60 days after intervention. Method of measurement: Global Acne Grading System (GAGS).

Secondary

MeasureTime frame
Changes in lesions count (total, inflammatory, non-inflammatory and regional). Timepoint: At baseline, 30 and 60 days after intervention. Method of measurement: visual counting.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAli Mohammadi

Shiraz university of medical science

dr.mohammadi71@gmail.com+98 917 736 9270

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026