Skip to content

Effect of training and creatine supplementation on cell apoptosis

Comparative effectiveness of 8 week resistance training and creatine supplementation on control of cell apoptosis in middle-aged men

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015091112386N2
Enrollment
30
Registered
2015-10-20
Start date
2015-10-01
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Encounter exercise for healthy admintation. Examination and encounter for administrative purposes

Interventions

Intervention 1: Control group: Maltodextrin supplementation every day 20 grams (4 times 5 gm) for one week, then every day 5 grams for 8 weeks. Intervention 2: Intervention group: Creatine supplementa
Placebo
Control group: Maltodextrin supplementation every day 20 grams (4 times 5 gm) for one week, then every day 5 grams for 8 weeks
Intervention group: Creatine supplementation every day 20 grams (4 times 5 gm) for one week, then every day 5 grams for 8 weeks

Sponsors

Islamic Azad University, Marivan Branch, Vice Chancellor for research of Islamic Azad University, Ma
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
40 Years to 70 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: males; nonathletic; aged 40-70 years; healthy; without consume any anti-inflammatory supplementation (during 6 months prior the study). Exclusion criteria: smoking; acute and chronic diseases such as diabetes; renal failure, atherosclerosis and hypertension, muscular injury and distrophy, uncontrolled intake of oxidative and anti-inflammatory drugs supplements and stimulants (during the study).

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Caspase-3. Timepoint: pre study, immediately after acute test following one week with or without creatine loading, immediately after acute test following 8 week with or without creatine loading. Method of measurement: ELISA.;Caspase-8. Timepoint: pre study, immediately after acute test following one week with or without creatine loading, immediately after acute test following 8 week with or without creatine loading. Method of measurement: ELISA.;Caspase-9. Timepoint: pre study, immediately after acute test following one week with or without creatine loading, immediately after acute test following 8 week with or without creatine loading. Method of measurement: ELISA.;Caspase-12. Timepoint: pre study, imminently after acute test following one week with or without creatine loading, imminently after acute test following 8 week with or without creatine loading. Method of measurement: ELISA.;IGF-1. Timepoint: pre study, immediately after acute test following one week with or without creatine loading, immediately after acute test following 8 week with or without creatine loading. Method of measurement: ELISA.;P-53. Timepoint: pre study, imminently after acute test following one week with or without creatine loading, imminently after acute test following 8 week with or without creatine loading. Method of measurement: ELISA.

Secondary

MeasureTime frame
Lactate. Timepoint: pre study, immediately after acute test following one week with or without creatine loading, immediately after acute test following 8 week with or without creatine loading. Method of measurement: ELISA.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactRahman Rahimi

Univerity of Kurdistan

rahman.rahimi@yahoo.com008733236782

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026