Effect of simple eye ointment on treatment of dry eye syndrome

Comparison of artificial tear drops and baby shampoos as treatments of dry eye syndrome(DES), with and without the administration of simple eye ointment

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2015090923952N1

Enrollment

Registered

2015-10-08

Start date

2015-09-01

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

dry eye syndrome. Lacrimal: cyst gland atrophy

Interventions

Intervention group: 1- Baby shampoo, every night, local, for 4 weeks 2- Artificial tear drop

Intervention 1: Control group: 1- Baby shampoo, every night, local, for 4 weeks 2- Artificial tear drop

in mild stages every 8 hours 1 drop in both eyes, and in moderate stages every 6 hours 1 drop in both eyes, for 4 weeks. Intervention 2: Intervention group: 1- Baby shampoo, every night, local, for 4

in mild stages every 8 hours 1 drop in both eyes, and in moderate stages every 6 hours 1 drop in both eyes, for 4 weeks 3- Simple eye ointment, every night, 0.5-1.0 cm2 in lower eyelid, in both eyes,

Treatment - Drugs

Control group: 1- Baby shampoo, every night, local, for 4 weeks 2- Artificial tear drop

in mild stages every 8 hours 1 drop in both eyes, and in moderate stages every 6 hours 1 drop in both eyes, for 4 weeks

in mild stages every 8 hours 1 drop in both eyes, and in moderate stages every 6 hours 1 drop in both eyes, for 4 weeks 3- Simple eye ointment, every night, 0.5-1.0 cm2 in lower eyelid, in both eyes,

Eligibility

Sex/Gender

All

Age

20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Patients with DES clinical signs and symptoms which are confirmed by TBUT test; Patients must be between 20 and 60 years old; Patients must be diagnosed with DES for first time; Patients with idiopathic DES, not secondary types; Patients' workplace must be indoor; Patients must not take any ophthalmic drugs so far; Disease progression must be staged as mild or moderate; No history of undergoing refractive errors surgeries, utilizing contact eye lens and any drugs associated to DES; Informed consent for being involved in the study Exclusion criteria: Refusal to keep participating in the study; Intolerance to treatment

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Patients remission rate. Timepoint: before Intervention, 2 weeks after intervention and 4 weeks after intervention. Method of measurement: International Dry Eye Workshop(DEWS).	—

Secondary

Measure	Time frame
Side effects of simple eye ointment. Timepoint: 1 month after intervention. Method of measurement: Standard questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHamid Mirhoseiny

Semnan University of Medical Sciences

mirhoseiny.hamid@gmail.com+98 23 3365 5404

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026