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Effect of low-calorie diets on anthropometric indices, glycemic markers and cardiovascular risk factors in metabolic syndrome

Effect of modified Alternate-Day Fasting (ADF) in contrast with Calorie Restriction (CR) on anthropometric indices, glycemic markers and cardiovascular risk factors in metabolic syndrome patients.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20150909023957N8
Enrollment
70
Registered
2019-01-23
Start date
2017-07-06
Completion date
Unknown
Last updated
2019-02-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

metabolic syndrome disease. Metabolic syndrome

Interventions

Sponsors

Vice Chancellor for Research, Isfahan university of medical sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
25 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patients with Metabolic Syndrome Age 25-60 years 25 =BMI =40 kg/m2 Body weight more than 5 kg has not changed during the last 3 months. No fasting for 3 months prior to the beginning of the study People who are willing to cooperate and answer questions and conduct their tests after explaining the work.

Exclusion criteria

Exclusion criteria: Smoker History of cardiovascular, pulmonary, renal, thyroid disorders, digestive and liver problems such as hepatitis and ... Follow a special diet Severe physical activity People who have been using drugs that have an effect on weight loss, lipid or glucose metabolism over the past 6 months.

Design outcomes

Primary

MeasureTime frame
Body weight and body composition analysis. Timepoint: Two times, before and after dietary intervention. Method of measurement: In light clothing, standing without shoes and hose on metal foot- plates while holding the handles of the bio-impedance analyzer (BIA; BC-418, Tanita Europe, Amsterdam, NL).;BMI. Timepoint: Two times, before and after dietary intervention. Method of measurement: BMI was calculated as the weight in kilograms divided by the square of the height in meters (kg/m2).;Waist circumference. Timepoint: Two times, before and after dietary intervention. Method of measurement: Waist circumference was measured by a flexible tape to the nearest 0.1 cm, in standing subject at the midway between the lower costal margin of the last palpable rib and the top of the iliac crest during a period of expiration.;Triglyceride (TG). Timepoint: Two times, before and after dietary intervention. Method of measurement: Plasma TG concentration was measured glycerol phosphate oxidase/peroxidase method.;Total cholesterol. Timepoint: Two times, before and after dietary intervention. Method of measurement: Plasma total cholesterol was measured in duplicate using cholesterol oxidase/peroxidase.;HDL cholesterol. Timepoint: Two times, before and after dietary intervention. Method of measurement: Plasma HDL-C were measured Detergent oxidase/peroxidase methods.;LDL cholesterol. Timepoint: Two times, before and after dietary intervention. Method of measurement: LDL-C concentration was calculated using the Friedwald equation (LDL= total cholesterol – TAG/ 2.18 – HDL).;Fasting blood sugar. Timepoint: Two times, before and after dietary intervention. Method of measurement: Fasting plasma glucose concentrations were measured using auto-analyzer (glucose oxidase/peroxidase).;Plasma insulin. Timepoint: Two times, before and after dietary intervention. Method of measurement: Plasma insulin levels were measured by Elisa method.;HOMA-IR. Timepoint: Two times, before and after dietary interve

Countries

Iran (Islamic Republic of)

Contacts

Public Contactarefe parvaresh

Isfehan university of medical science

a.p.nutrition86@gmail.com+98 35 3726 2557

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026