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Effect of low calorie diets on inflammation in metabolic syndrome

Effect of Modified Alternate-Day Fasting (ADF) in contrast with Calorie Restriction (CR) on inflammatory index and coagulation factors in metabolic syndrome patients.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20150909023957N7
Enrollment
70
Registered
2018-12-18
Start date
2017-07-06
Completion date
Unknown
Last updated
2019-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

metabolic syndrome disease. Metabolic syndrome

Interventions

Sponsors

Vice Chancellor for Research, Isfahan University of Medical Sciences
Lead Sponsor
Food Security Research Center
Collaborator

Eligibility

Sex/Gender
All
Age
25 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patients with Metabolic Syndrome Age 25- 60 years 25 =BMI = 40 kg/m2 Body weight more than 5 kg has not changed during the last 3 months. No fasting for 3 months prior to the beginning of the study People who are willing to cooperate and answer questions and conduct their tests after explaining the work.

Exclusion criteria

Exclusion criteria: Smoker History of cardiovascular, pulmonary, renal, thyroid disorders, digestive and liver problems such as hepatitis and ... Follow a special diet Severe physical activity People who have been using drugs that have an effect on weight loss, lipid or glucose metabolism, inflammatory condition and coagulation factors over the past 6 months.

Design outcomes

Primary

MeasureTime frame
Serum High- Sensitivity- C- Reactive Protein (Hs- CRP). Timepoint: Two times, before and after dietary intervention. Method of measurement: Serum hs- CRP concentration was assayed using ELISA kits (LDN, Nordhorn, Germany).;Fibrinogen. Timepoint: Two times, before and after dietary intervention. Method of measurement: Fibrinogen was also measured using immunoturbidimetry tests (Pars Azmoon. Co., Iran).;PT (Prothrombine Time). Timepoint: Two times, before and after dietary intervention. Method of measurement: PT was tested using (PT- based) Prothrombin Clot-Based Assay (sec) method.;A-PTT (activated limited thromboplastin time). Timepoint: Two times, before and after dietary intervention. Method of measurement: a- PTT was tested using (PT- based) Prothrombin Clot-Based Assay (sec) method.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactRoghaye sadat razavi

Isfahan University Of Medical Sciences, School of Nutrition and Food Science

forogh_1369@yahoo.com+98 35 3726 2557

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026